ID   LPTD_MANSM              Reviewed;         783 AA.
AC   Q65PZ6;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=MS2357;
OS   Mannheimia succiniciproducens (strain MBEL55E).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Basfia.
OX   NCBI_TaxID=221988;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBEL55E;
RX   PubMed=15378067; DOI=10.1038/nbt1010;
RA   Hong S.H., Kim J.S., Lee S.Y., In Y.H., Choi S.S., Rih J.-K., Kim C.H.,
RA   Jeong H., Hur C.G., Kim J.J.;
RT   "The genome sequence of the capnophilic rumen bacterium Mannheimia
RT   succiniciproducens.";
RL   Nat. Biotechnol. 22:1275-1281(2004).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; AE016827; AAU38964.1; -; Genomic_DNA.
DR   RefSeq; WP_011201502.1; NC_006300.1.
DR   AlphaFoldDB; Q65PZ6; -.
DR   SMR; Q65PZ6; -.
DR   STRING; 221988.MS2357; -.
DR   EnsemblBacteria; AAU38964; AAU38964; MS2357.
DR   KEGG; msu:MS2357; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000000607; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..783
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000020282"
SQ   SEQUENCE   783 AA;  90161 MW;  EFE1F712A46E36FA CRC64;
     MKKNYYSLIS FSIFTALYST AGFADLQQQC LAGVPQFSGE VVKGNANEMP VYIEADKAEL
     NHPTKGVYQG NVDIKQGNRH LITETAEIIQ SGQDENVQRY AYAKGGFDYK DNIINLTGDD
     AKVHLNTKDT DVKNADYQFV GRQGRGSAQS AEVREDYRLL NNATFTSCLP NDNSWQIEAK
     EMKQYIKEEY AEMWHARFKV AGVPVFYTPY LQLPIGDRRR SGLLIPSAGS SSRDGYWYSQ
     PIYWNIAPNY DATFTPKYMT HRGWQMNGEF RYLNEIGEGK IAGEYLGDDR YKDYIGDNKS
     RHLFYWAHNA KLFDNWRLNV NYTKVSDKRY FSDFDSDYGS STDGYATQTA RLAYFQPNYN
     FAISAKQYQV FDEVSVGPYK ALPQIDFNYY QNDLAQGLLD FKLFAQAVRF ENDSTLMPTA
     WRYHAEPSLN LPMSNQYGSL NVETKLYATH YEQRKGSSAR AEDIDRSVNR MIPQIKVDLQ
     TVLASDKTFV DGFTQTLEPH LQYLYRPYRD QSNIGSKRNT EYLGYGYDSA LLQQDYFSLF
     RDRRYSGLDR IASANQFTLG GTTRFYDEQA NERFNLSLGQ ILYLNDSRID NNSDHSTSGR
     ASSWALESNW KLSDQWNWRG SYQYDTRLNE TSLANTTLEY NPEKNNLIQL NYRYASQAYI
     DQNLTSGANR YNQDIKQIGT TIAWEVSDNW VLVGRYYHDI ALNKLVEEYA GIKYNTCCWS
     VGVGARRHLV SKSNYTYSAN KDTIYDNSFG ITFELRGLGN EQHSGIVDML DKGMLPYVKP
     FNL