ID   LPTD_NEIG1              Reviewed;         801 AA.
AC   Q5F651;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=NGO1715;
OS   Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=242231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700825 / FA 1090;
RA   Lewis L.A., Gillaspy A.F., McLaughlin R.E., Gipson M., Ducey T.F.,
RA   Ownbey T., Hartman K., Nydick C., Carson M.B., Vaughn J., Thomson C.,
RA   Song L., Lin S., Yuan X., Najar F., Zhan M., Ren Q., Zhu H., Qi S.,
RA   Kenton S.M., Lai H., White J.D., Clifton S., Roe B.A., Dyer D.W.;
RT   "The complete genome sequence of Neisseria gonorrhoeae.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; AE004969; AAW90336.1; -; Genomic_DNA.
DR   RefSeq; WP_003698952.1; NC_002946.2.
DR   RefSeq; YP_208748.1; NC_002946.2.
DR   AlphaFoldDB; Q5F651; -.
DR   SMR; Q5F651; -.
DR   STRING; 242231.NGO_1715; -.
DR   PRIDE; Q5F651; -.
DR   EnsemblBacteria; AAW90336; AAW90336; NGO_1715.
DR   KEGG; ngo:NGO_1715; -.
DR   PATRIC; fig|242231.10.peg.2051; -.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   Proteomes; UP000000535; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   Pfam; PF04453; LptD; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           24..801
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281618"
SQ   SEQUENCE   801 AA;  87541 MW;  F1B4179D5BF5E8DD CRC64;
     MARLFSLKPL VLALGFCFGT HCAADTVAAE EADGRVAEGG AQGASESAQA SDLTLGSTCL
     FCSNESGSPE RTEAAVQGSG EASVPEDYTR IVADRMEGQS KVKVRAEGSV IIERDGAVLN
     TDWADYDQSG DTVTVGDRFA LQQDGTLIRG ETLTYNLDQQ TGEAHNVRME TEQGGRRLQS
     VSRTAEMLGE GRYKLTETQF NTCSAGDAGW YVKAASVEAD RGKGIGVAKH AAFVFGGVPL
     FYTPWADFPL DGNRKSGLLV PSVSAGSDGV SLSVPYYFNL APNFDATFAP GIIGERGATF
     DGQIRYLRPD YSGQTDLTWL PHDKKSGRNN RYQAKWQHRH DISDTLQAGV DFNQVSDSGY
     YRDFYGGEEI AGNVNLNRRV WLDYGGRAAG GSLNAGLSVQ KYQTLANQSG YKDEPYAIMP
     RLSADWHKNA GRAQIGVSAQ FTRFSHDGRQ DGSRLVVYPG IKWDFSNSWG YVRPKLGLHA
     TYYSLDSFGG KASRSVGRVL PVVNIDGGTT FERNTRLFGG GVVQTIEPRL FYNYIPAKSQ
     NDLPNFDSSE SSFGYGQLFR ENLYYGNDRI NAANSLSTAV QSRILDGATG EERFRAGIGQ
     KFYFKDDAVM LDGSVGKNPR SRSDWVAFAS GGIGGRFTLD SSIHYNQNDK RAEHYAVGAG
     YRPAPGKVLN ARYKYGRNEK IYLQADGSYF YDKLSQLDLS AQWPLTRNLS AVVRYNYGFE
     AKKPIEMLAG AEYKSSCGCW GAGVYAQRYV TGENTYKNAV FFSLQLKDLS SVGRNPAGRM
     DVAVPGYIPA HSLSAGRNKR P