ID   LPTD_NITEC              Reviewed;         725 AA.
AC   Q0AGR1;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Neut_1216;
OS   Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=335283;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 101675 / C91 / Nm57;
RX   PubMed=17991028; DOI=10.1111/j.1462-2920.2007.01409.x;
RA   Stein L.Y., Arp D.J., Berube P.M., Chain P.S., Hauser L., Jetten M.S.,
RA   Klotz M.G., Larimer F.W., Norton J.M., Op den Camp H.J.M., Shin M., Wei X.;
RT   "Whole-genome analysis of the ammonia-oxidizing bacterium, Nitrosomonas
RT   eutropha C91: implications for niche adaptation.";
RL   Environ. Microbiol. 9:2993-3007(2007).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000450; ABI59471.1; -; Genomic_DNA.
DR   RefSeq; WP_011634291.1; NC_008344.1.
DR   AlphaFoldDB; Q0AGR1; -.
DR   SMR; Q0AGR1; -.
DR   STRING; 335283.Neut_1216; -.
DR   EnsemblBacteria; ABI59471; ABI59471; Neut_1216.
DR   KEGG; net:Neut_1216; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000001966; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           26..725
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_5000132405"
SQ   SEQUENCE   725 AA;  82357 MW;  C55469D5AEA675E5 CRC64;
     MSLLSKLHLI LYICLLLLPL RFVNAEQLSG SGESQPVHIE ADRIDGHYQQ EIEATGNVRM
     RRGDQTLSAD HVKYYQDTED VEVKGNALLE RPDDTLWGTF LQMNLQTDIG ELRDPRYALK
     GGNGRGSGSL LLLEGENQYR IKKARYTTCP EDNHDWYILA DDLEIDNEKK VGTARHASIR
     FKDVPILYLP WMNFSFSKER KTGFLSPIMG NTSRSGVEVS VPFYWNIAPN YDATITPRLM
     SRRGVMLDNE FRYIGQGLGG RLQFDYLPND LVTDTTRYGL QFNHSQFLGS GWFGALNYNR
     VSDHNYFRDL GNNILFTSQV NLLQQATASY FSELGRNGML TFSTLMQQFQ TVQDPRAPII
     SPFKILPRFT LNAVKSNVYG LDFDLASSFT HFSHPTLPHG LRFTAFPSVA LPLENSFGFI
     RPRVGLHYTK YDLNTPAFPG TNDKHPDRSV PIFSLDSGVV LERDMTLGGG NFIQTLEPRV
     FYTYIPYREQ RLLPNFDSAE MDFSFAQLFM EKRFSGEDRI NDANEITLAM SSRLIHSATG
     NERLRFSVGQ RIRFSDRRVL LTSPQVTRAG SDFIAELSGS LAQHVKTDAG IQLNQNNLLI
     EKIRTGISYN PAPGQVINAG YRFTRDVLEQ VDLSTQWPFL KRWQGFAAIN YSLKNDKLLA
     GLLGLEYNAC CWSLRLVASR FTTATQKTST NIFVQLELND LMRIGTNPIR VLQQSIPGYV
     RTDLQ