ID   LPTD_NITEU              Reviewed;         723 AA.
AC   Q82W18;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=NE0881;
OS   Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC
OS   14298).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=228410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298;
RX   PubMed=12700255; DOI=10.1128/jb.185.9.2759-2773.2003;
RA   Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L.,
RA   Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A.,
RA   Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.;
RT   "Complete genome sequence of the ammonia-oxidizing bacterium and obligate
RT   chemolithoautotroph Nitrosomonas europaea.";
RL   J. Bacteriol. 185:2759-2773(2003).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL954747; CAD84792.1; -; Genomic_DNA.
DR   RefSeq; WP_011111492.1; NC_004757.1.
DR   AlphaFoldDB; Q82W18; -.
DR   SMR; Q82W18; -.
DR   STRING; 228410.NE0881; -.
DR   EnsemblBacteria; CAD84792; CAD84792; NE0881.
DR   KEGG; neu:NE0881; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   PhylomeDB; Q82W18; -.
DR   Proteomes; UP000001416; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           24..723
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281621"
SQ   SEQUENCE   723 AA;  82766 MW;  A8164BCB92F8B34C CRC64;
     MNTLKLCLIL YACLVLLPVR VMSADLSPAS SERQPIYIEA DHIDGHYQQE IEAIGNVRMR
     RGDQTLTADR VKYYQSNENV EVEGNAQLER PDDILWGSYL QMNLNDNTGQ LSEPRYLQKD
     GNGRGDGNLL LLEGENQYRF KKARYTTCPE DDHDWYILAD DLEIDKEKKV GTARHASVRF
     KDVPILYVPW MNFSFGNERK TGFLSPIMGN TSRSGVEVSV PFYWNIAPNY DATITPRLMS
     RRGVMLNNEF RYIGQTLNGR FLLDYLPNDL ETDTTRYGMQ LNHFHNLGAG WFGMINYNSA
     SDRNYFRDLG NNILFTSQTN LLQQGFASYF RELGRNGTLT FSTLLQQFQT LQDPRAPIIS
     PFKILPRFTL NAAKRNVYGL DFDFSGSFTH FSHSTLPHGL RTTFLPGVSL PLENSFGFIR
     PRVSLHHTRY DLNEPANPAA NDKHLSRTVP IFSFDSGIVL ERDTTLAREN FVQTIEPRVF
     YTYIPYRDQQ LLPNFDSAEM DFSYPQLFLE RRFSGEDRIN DANEITLAVS SRLIHSATGN
     ERLRFSAGQR IRFSDRRVIL TSPQVTRAGS DFIAELSGGI TQNIKTDTGI QLNQNNFLIE
     KIRTGISYRP APGKVINAGY RFTRDVLEQV DLSTQWPFLK KWQGFAAINY SLKDDKLLAG
     LLGLEYNACC WSLRFVTSHF TTATQRTSTN IFVQLELNDL MRIGTNPVRV LQQTIPGYMR
     TDL