ID   LPTD_NITMU              Reviewed;         929 AA.
AC   Q2YBP2;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Nmul_A0521;
OS   Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=323848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25196 / NCIMB 11849 / C 71;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT   25196.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000103; ABB73829.1; -; Genomic_DNA.
DR   RefSeq; WP_011379883.1; NZ_FNVK01000001.1.
DR   AlphaFoldDB; Q2YBP2; -.
DR   SMR; Q2YBP2; -.
DR   STRING; 323848.Nmul_A0521; -.
DR   PRIDE; Q2YBP2; -.
DR   EnsemblBacteria; ABB73829; ABB73829; Nmul_A0521.
DR   KEGG; nmu:Nmul_A0521; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000002718; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   Pfam; PF04453; LptD; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..929
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_5000101393"
FT   REGION          26..208
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..70
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..208
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   929 AA;  103017 MW;  E38A5D27138D48A7 CRC64;
     MKLRFIRSAG WLFLLFCLAC NARADLPPLS SKPEQGRATP SGEGDDKPVV IDTERIRGHH
     EYESGTRSES ELRSRSTIST DQIKKPNQKA DPAAKDTPSA PQQNYTLSPA IKTDSRTGTS
     AQESEKAESM VLPGGVERLP GPAAEEGEPR LRTRTQSAPR TLSAQKRGEK PAKTPAPAEA
     DQDRPGFAEG ERIGGHREEA GDEKLRLAGE TEPEAIEQKL AEAEAETDKQ SPVFVVADRL
     QGHVEEEIEA IGKAELSAGP QFISAERMKY NQGTNDAEAQ GNVRVEKEGD ILEGSDLKFN
     LLSKTGQLSE PSYRLKDASS RGYAGMLLFE GENQYRLQKA SYTTCPVGDD SWVLQVADLK
     LDNDKKVGTA KNVKLTFKDV PILYTPWMNF SYSGERKSGL LAPTYGTGSR TGLELAVPFY
     WNIAPNYDAT FSARLMSKRG LAINNEFRFL GQNSSSNLLA DIVPRDLDTQ TTRWRTSFWH
     NHYLGAGFSA RLDYNRVSDA TYFRDFGNNL NLTSRTNLLQ QGLLSYNRGL GDDGTFNVTS
     LVQSFQTIQD PLAAIVVPYK RLPQVGLNAN KPDVFGTGVD VNLSGSWTNF SHPTLVNGSR
     TVLFPSMSYP LRNSFGFITP KVGMHYTRYS LGEGAGVSEE NPTRTLPIFS LDSGLAFDRK
     MSLGGESFTQ TLEPRVFYVY VPFRAQDQLP NFDSAKTDFS FAQMLAENRF SGSDRINDAN
     QVTFALTTRL LESSTGRERL RLAVGHQLSF IDRRITLETP QTIDRRPDFI AAVSGFLTPT
     ISTDTSFQFD QTRLLADVVR SGVSYRPEPG RVLNFGYRFT RDVLHQVDAS SQWRWSERWQ
     TVARLNYSLQ DKRILEGLAG VEYNACCWSL RFVLQHLTLA TQKSTTAAFL QLELNGLMQI
     GSNPLTVLQR SIPGYIRTGS QGSGLIEGP