ID   LPTD_PARXL              Reviewed;         789 AA.
AC   Q145L4;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Bxeno_A0437; ORFNames=Bxe_A4024;
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400;
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M., Lao V.,
RA   Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A., Marx C.J.,
RA   Parnell J.J., Ramette A., Richardson P., Seeger M., Smith D., Spilker T.,
RA   Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B., Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome
RT   shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000270; ABE28975.1; -; Genomic_DNA.
DR   RefSeq; WP_011486801.1; NZ_CP008760.1.
DR   AlphaFoldDB; Q145L4; -.
DR   SMR; Q145L4; -.
DR   STRING; 266265.Bxe_A4024; -.
DR   EnsemblBacteria; ABE28975; ABE28975; Bxe_A4024.
DR   KEGG; bxb:DR64_1701; -.
DR   KEGG; bxe:Bxe_A4024; -.
DR   PATRIC; fig|266265.5.peg.461; -.
DR   eggNOG; COG1452; Bacteria.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   Pfam; PF04453; LptD; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..39
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           40..789
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281597"
SQ   SEQUENCE   789 AA;  86740 MW;  DCEF22EC4069F4ED CRC64;
     MPPRQLSQTT PSCAVVPRKR RLVAALIAVP GLMPALAHAQ LVGEAAQPQP IDAPWGMQLA
     PQLEERPLQP GQKPATFVLG DTTSGTTDQD MAAKGSAEVR RNTVVIKADA LHYDQDTDMA
     DAYGSVHVVN NGNSFVGPEA HMRVDSSEGF MTAPKYHFNV TGGSGSAERV DLLDNERSVF
     TKGTYTACAC ADDPAWYIKG SEFDFDTGAD EGVAHNGVLF FQGFPVFASP WLSFPLSGER
     RSGVLPPTFS LSSSNGFELS VPYYFNIAPN RDLTLTPRLI SKRGVQLQST FRYLSPTYSG
     SITGEFLPDD HLTKTNRYAL YIQHNQNFGN GFGGYIYYNK VSDNTYPEDL SSSVNQFMNG
     TQLLYQQEAG LTYNNGPWSV LAREQHWQTL TPSVAPYGRE PQLNVKYAKY NVGGFDYGAE
     ADYSNFRITT ADMTQGQRVM FNPYLSYSVV GPGYFVTPKV QWHFASYNLN HLSDADVAAG
     TPKNFTESIP TLTFDTGLVF DRSVRIFGQD YIQTLEPRLY YVYTPYRNQQ SAPLFDTADS
     DFGLAEIFTP NTFVGNDRIA DANRLTAALT TRFIDAATGD ERARFVIAQQ YYFQDQRVTL
     QSTQTSAQAT HSDLIAGASL KLGAGFASET AFQYNADNNQ LVKTSVGFGF SPATGKVINV
     AYRYTRANTT LDNTPINQVL ISGQWPLAHR VYGVGRFNYD LGGHRIVDGL VGLQYDADCW
     TLGAGIQRYA NGLNTSGQNQ SSTRFLAQLT FKGLSSVDNG LMTAFRSSVA GYTPLPPPPP
     PESRFTNYE