ID   LPTD_PECAS              Reviewed;         787 AA.
AC   Q6D0E3;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=ECA3856;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; BX950851; CAG76754.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6D0E3; -.
DR   SMR; Q6D0E3; -.
DR   STRING; 218491.ECA3856; -.
DR   EnsemblBacteria; CAG76754; CAG76754; ECA3856.
DR   KEGG; eca:ECA3856; -.
DR   PATRIC; fig|218491.5.peg.3911; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..787
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000020279"
SQ   SEQUENCE   787 AA;  89433 MW;  EBA796AD2815A947 CRC64;
     MKKSFPTLLA TLVWSALYSQ HALADLAEQC MLGVPTYNRP LVTGDPNQLP VNIQADKTEA
     NYPDNAKFIG NVNIQQGNSI MTAEQVELSQ LDPATQGSTP TRTITATGKV HYDDNQVILK
     GPKAWANLNT KDTDVYEGDY QMVGRQGRGS ADKMKMRDSN RYTILENGSF TSCLPGDNSW
     SVVGSEVIQD REEQVAEIWN ARFKIGGVPV FYSPYLQLPI GDKRRSGFLI PNAKYGSSNG
     FELLTPYYWN IAPNFDATIT PHLQTKRGMQ WQNEFRYLTT PGLGVIQFDW LPSDSEYAKT
     SQQDNNDTRW LLHWGHSGVM DQVWRFDADY TKVSDDRYFT DLDSHYGSTT DGYVTQKLST
     GYANQNWNTT LSTRQFQVFS NATSRDVYRA EPQLDINYYQ NDIGPVDMHL YGQAVKFTNV
     NDNRPEATRL HVEPTLNLPL ANRWASLNTE AKLLATHYQQ DNLDRYRADP TVSDVNKNAL
     QSSVNRVMPQ YKVDGKMVFE REMDWSQAYT QTLEPRAQYL YVPYRDQSSI HTYDSTLMQT
     DYSGLFRDRS YSGLDRIASA NQIATGVTTR IYDDALVERF NASIGQIYYF DRPRTGDRNT
     SLDKSDNNGS QVWAGDSFLK IDDSWGVRGG LQYDNRLNEV ALGDAVLEYR RDAERLVQLN
     YRYASPEYIR DMLPNVTNQG SQQGISQVGV TASWPIVERW AVVGAYYYDT KANQPANQLI
     GLQYNTCCWA VSVGYERKIT DWNSASRSSE YDNKVSFNIE LRGLSSNYGL GSDKMLRSGI
     LPYQRAF