LPTD_PHOLL
ID LPTD_PHOLL Reviewed; 774 AA.
AC Q7N8V4;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN OrderedLocusNames=plu0612;
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01;
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000255|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
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DR EMBL; BX571860; CAE12907.1; -; Genomic_DNA.
DR RefSeq; WP_011144989.1; NC_005126.1.
DR AlphaFoldDB; Q7N8V4; -.
DR SMR; Q7N8V4; -.
DR STRING; 243265.plu0612; -.
DR EnsemblBacteria; CAE12907; CAE12907; plu0612.
DR GeneID; 24168041; -.
DR KEGG; plu:plu0612; -.
DR eggNOG; COG1452; Bacteria.
DR HOGENOM; CLU_009039_2_0_6; -.
DR OMA; DYSHLDW; -.
DR OrthoDB; 100018at2; -.
DR BioCyc; PLUM243265:PLU_RS03015-MON; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Reference proteome; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT CHAIN 25..774
FT /note="LPS-assembly protein LptD"
FT /id="PRO_0000020284"
SQ SEQUENCE 774 AA; 89022 MW; F010BB264E723A3C CRC64;
MKKCYPTLLA TTVWAALYGQ YAHADLAAQC MLGIPVYDQP IINGDLNQLP INILADDSRA
DYPRSAKFIG NVNIKQGNKT LTADQVQLDQ TEDKVPLRTV TATGNVHYDD PLIILKGPRA
WSNLNNKDTD MYQSDYQMVG RQGRGTADKM KLRGENRYAI LDNGTFTSCL PGNDSWSVVG
SEVILDREEE VAEIWNARFR VANVPIFYSP YLQLPIGNKR RSGFLIPNAS YSKNDGFEFL
LPYYWNIAPN YDATITPHYI SKRGLKLDNE FRYLTKAGTG TLALDWLNND EQYVKDKKTN
TRTARESDNR WLFYWRHSGV MDRVWRFNID YTKVSDPEYF SDFSSQYGST TDGYATQKFS
LGYAQQNWNA TLSTKQFQIF SKDTSRKAYR AEPQLDLNYY KNDLGPFDLK VYGQAAKFTS
VGKNNPEATR WHLEPSINLP LSNGWASMNN EVKLMATHYQ QDIPKATENA EYKESVNRVL
PQFKSEAKMV FERSTYLNNN YTQTLEPQVQ YLYVPYKDQD NINNFDSSLL QTDYNGLFRD
RFYGGLDRIS SANQVTTGLT TRIYDESLVE RFNLSLGQIY YFERPRTGKE TIINSKDSTG
MMTWAGDTYW KINDSWGLKG GMQYDTRLGN VTMGNAVLEY RRDEDRLVQL NYRFVDRDYI
QATAKSAPAF QQGISQVGLV ASWPLSERWG LVGAYYYDTK EQQPASQLVG LQYNTCCWAI
NVGYERKIVG WKDNNSEYDN KWSFNFELRG LSNNHSLGSR KMLQSGIMPY QRAF