ID   LPTD_POLSJ              Reviewed;         822 AA.
AC   Q121Q3;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Bpro_4863;
OS   Polaromonas sp. (strain JS666 / ATCC BAA-500).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Polaromonas; unclassified Polaromonas.
OX   NCBI_TaxID=296591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JS666 / ATCC BAA-500;
RX   PubMed=18723656; DOI=10.1128/aem.00197-08;
RA   Mattes T.E., Alexander A.K., Richardson P.M., Munk A.C., Han C.S.,
RA   Stothard P., Coleman N.V.;
RT   "The genome of Polaromonas sp. strain JS666: insights into the evolution of
RT   a hydrocarbon- and xenobiotic-degrading bacterium, and features of
RT   relevance to biotechnology.";
RL   Appl. Environ. Microbiol. 74:6405-6416(2008).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000316; ABE46739.1; -; Genomic_DNA.
DR   RefSeq; WP_011485724.1; NC_007948.1.
DR   AlphaFoldDB; Q121Q3; -.
DR   SMR; Q121Q3; -.
DR   STRING; 296591.Bpro_4863; -.
DR   EnsemblBacteria; ABE46739; ABE46739; Bpro_4863.
DR   KEGG; pol:Bpro_4863; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000001983; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   Pfam; PF04453; LptD; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..37
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           38..822
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_5000117340"
FT   REGION          38..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   822 AA;  91327 MW;  CE07F7C6B209035F CRC64;
     MRRASRSPFI LSPVAHAVSR LVLCATLGWT YAGSGHAQVP APAGGSEVPL GARPPASAPV
     AAQQETPLKL KSSPALAEEV PNGPGDEGPT FVFGDSVSGR PNLETVIDGN AELRRGATSI
     RADRIEYYQP EDRVKSRGNV RINNAGNRFE GPELEITLDR FEGFFTQPRY RFLSNGGNGQ
     AERVDFIDDK HLTAHRASYT TCERDNEASW KPAWELRARS FEFDFDEEVG VANGAVLRFK
     NVPILGFPKF SFPLSDKRKS GLLPPTLNMS SVNGFEVRQP YYFDIAPNRD ATFSPAIMTK
     RGVDLAGEFR YLEPTYKGEL RANILPGDKL RNRDRWSYGY QHSGTIDSGL SAIGNLGVNL
     NLSRVSDNDY WRDFPIASNS TTQRLLAQDA TVSWNRGFFA AAVRTLKWQT LQDLSAPIVP
     PYDRLPQFTA NYTRVDAPLL GLGRGFDWSV EGDYTRFSAD RTLTGQPNSN RAFTRAQLSH
     PWLSPAGFIT PKMQLHATSY QFDAPLVNGA RSASRTVPTF SLDSGLQFER QAGFLGRSFT
     QTLEPRAFYV RTPYRDQSLL PNYDSGANDF NFATVFTENA FVGNDRISDA NLLTLGVTSR
     LLDPATGAEA VRVGVAQRLR FADQRVTLPG ALPITDRISD LLVGASVNWV PQWSFDSTVQ
     YNPKTKQSER SSIGVRYNPG NYRVISAAYR RQRNISEQID VGWQWPLNDL WGDKGRDLGA
     GQGQGGGRYY AVGRLNYSVP DRKLVDAIVG VEYDGCCWIG RVVLQRTQNG TATSDTRILF
     QLELVGFSRI GANPLETLKS NVPRYQYLRE KINTPSRFTT YD