ID   LPTD_PSEPF              Reviewed;         937 AA.
AC   Q3K5T5;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Pfl01_5132;
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pf0-1;
RX   PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA   Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA   Jackson R.W., Preston G.M., Zhang X.-X., Moon C.D., Gehrig S.M.,
RA   Godfrey S.A.C., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA   Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA   Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA   Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA   Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT   "Genomic and genetic analyses of diversity and plant interactions of
RT   Pseudomonas fluorescens.";
RL   Genome Biol. 10:R51.1-R51.16(2009).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000094; ABA76869.1; -; Genomic_DNA.
DR   RefSeq; WP_011336205.1; NC_007492.2.
DR   AlphaFoldDB; Q3K5T5; -.
DR   SMR; Q3K5T5; -.
DR   STRING; 205922.Pfl01_5132; -.
DR   EnsemblBacteria; ABA76869; ABA76869; Pfl01_5132.
DR   KEGG; pfo:Pfl01_5132; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_1_0_6; -.
DR   OMA; DYSHLDW; -.
DR   Proteomes; UP000002704; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           34..937
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_5000002507"
FT   REGION          58..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   937 AA;  105602 MW;  7A9EA025B34DF2FB CRC64;
     MALKSPAFRK KFPLLVTGSL LAMQPLASSF VVAAEQYDCA VSATGGWACS PKTPAAALPP
     RPVHDGSAVS AAGEAPAESG STAESGPKPV LVTESKGRGL KSRSEDYSHL DWVPREKLTA
     AQLAETGPYC SGSYIEPIRP GMNDKTNKSD APTFIGAKAS RYQQDSQVAS LAGDVVMRQG
     SMQVEADEAN LYQAESRGEL AGNVRIRDNG ALIVGDHADV QLDTGEAKVD NAEYVMHKSR
     IRGNALYAKR AENAIIRLKD GTYTTCEPNS NAWQLKGNNI TLNPATGFGT ATNVTLRVKD
     IPVLYTPYIY FPIDDRRQSG FLPPTIGTGS DTGFMLVTPY YFNLAPNYDA TLYPRYMAKR
     GLLMEGEFRY LTKSSEGQFG AAFLNDEETE RSKQTDYQKN RYMYNWQHKG GLDSRVFTQV
     DYTKISDPYY FQDLQTDQIG VKSADFVNQQ GSVTYRGDNY TARLNAQAYQ LATVSNITPY
     DRLPQITFNG QLPYHPEGLN FDYETEVVRF DRDLQNGNFV NEDGTVERRL DNNVIGLARA
     NGDRLNLKPS VSLPLNWTYG FLKPSLKYQY TQYQLDLDGT GKSQIVAQQN AAAATGTRYV
     GGEFGSSQNR GVPIASIDGG LYFDRNTTWF GKNYRQTLEP RLFYLYVPEK DQEDIPVFDT
     SEYTFNYASL FRDNRFSGSD RVGDENKLSL GIDNRWIEED GFERQRISIG QALYFKDREV
     QLPGIDPKTR DDAHSNVSPY ALEYEYRWNR DWRTTADYNW DPDSRSPRSG SAMLHYQPED
     NPNKVVNVGY RYRNDQVRYD QNTGKWSVGG GDYGTPGQPG YVKDYYKIQQ HDFSVIWPIV
     PQWSAISRWQ YDYNRNRTLE AFGGFEYDNC CWKLRLINRY WVSYDEFSQN APENEKGDHG
     VFLQIVLKGL GGLTGAKVES FLDKGIQGYR QREDQAF