ID   LPTD_SACD2              Reviewed;         860 AA.
AC   Q21MS7;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Sde_0740;
OS   Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Cellvibrionales;
OC   Cellvibrionaceae; Saccharophagus.
OX   NCBI_TaxID=203122;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2-40 / ATCC 43961 / DSM 17024;
RX   PubMed=18516288; DOI=10.1371/journal.pgen.1000087;
RA   Weiner R.M., Taylor L.E. II, Henrissat B., Hauser L., Land M.,
RA   Coutinho P.M., Rancurel C., Saunders E.H., Longmire A.G., Zhang H.,
RA   Bayer E.A., Gilbert H.J., Larimer F., Zhulin I.B., Ekborg N.A., Lamed R.,
RA   Richardson P.M., Borovok I., Hutcheson S.;
RT   "Complete genome sequence of the complex carbohydrate-degrading marine
RT   bacterium, Saccharophagus degradans strain 2-40 T.";
RL   PLoS Genet. 4:E1000087-E1000087(2008).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000282; ABD80002.1; -; Genomic_DNA.
DR   RefSeq; WP_011467223.1; NC_007912.1.
DR   AlphaFoldDB; Q21MS7; -.
DR   SMR; Q21MS7; -.
DR   STRING; 203122.Sde_0740; -.
DR   EnsemblBacteria; ABD80002; ABD80002; Sde_0740.
DR   KEGG; sde:Sde_0740; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000001947; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           22..860
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_5000111110"
SQ   SEQUENCE   860 AA;  95019 MW;  C348B9335830EAA7 CRC64;
     MTKRYFSLLA VCSAIATSTF ADDTPTNSLS LGKTYLRCYP QADSNQWDCA EYSSETNLPI
     GRSQIQQAPN AYDFVSAENL TPAAQSALLP GCTGMYIDPL GDQTNAPSPE NTPLIVEADD
     SVLTGSQKAQ LDGNVQISQG ARSIRADSMT YSRETEEASL AGGVTIRNPG LLIRGDKASM
     STTRNQASFE NAIFVLHGQH IRGQADAIRQ TSDSSIVLEG GSITSCEPGS NAWSLGGAEI
     KIDNEKGQGT GKHITLKVGK VPIMYVPYIA FPLGDQRQSG LLFPSISSSD NGGLDAAVPF
     YWNMAPNYDA TITPRIISGR GAMLEVEGRH LNKSFYTESN IAYLPNDDGG QDKDLDTLVS
     NGDITESQAH PYTGQNRWLG HLSQQGGSAS NGGWYSTIDF TKVSDQDYFR DLGASSFSEQ
     NQSYLDQRAE LGYLFEHWTV SAMAQNRQVL LYDLDTPYRR APQLNAIGHY SVNGFEFKLD
     NELVRFDHPS NEWRNGDTLI TGSRLSTDYR AAWPIRGRWG FIKPEVGYKA LGYQLESDGL
     ASSAESSPTL GAAQASIDMS VIFEHRGGSI MQTIEPRVYY LHRAYTDHSD LYAVTADGQN
     VNFDTSIRTF SYSQLFRDSR FGGRDRLDDA NQTTVGLTSR WYSNNSGREL FSASIGQVFH
     NADRRVGLNG EELNTGQTSE LAADVSVMLG PLSRFYVNSI YDTEAAEITR ASSGVYYHSQ
     DLSTLANLSY SYVRDYRQSS IAAGTTEATD IDQVDLSFVT PINKQWSLMG RYNYDFTQAQ
     ELETFLGFEY NDCCYRVRLL ARKWLDSNIA SLTDNHDLEH DQGVFFEVHF KGLGGSGAKV
     NSILEDSIRG YQERERRNKQ