ID   LPTD_SODGM              Reviewed;         780 AA.
AC   Q2NVX3;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=SG0427;
OS   Sodalis glossinidius (strain morsitans).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Bruguierivoracaceae; Sodalis.
OX   NCBI_TaxID=343509;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=morsitans;
RX   PubMed=16365377; DOI=10.1101/gr.4106106;
RA   Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA   Aksoy S.;
RT   "Massive genome erosion and functional adaptations provide insights into
RT   the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL   Genome Res. 16:149-156(2006).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; AP008232; BAE73702.1; -; Genomic_DNA.
DR   RefSeq; WP_011410290.1; NZ_LN854557.1.
DR   AlphaFoldDB; Q2NVX3; -.
DR   SMR; Q2NVX3; -.
DR   STRING; 343509.SG0427; -.
DR   EnsemblBacteria; BAE73702; BAE73702; SG0427.
DR   KEGG; sgl:SG0427; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   BioCyc; SGLO343509:SGP1_RS03890-MON; -.
DR   Proteomes; UP000001932; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..780
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281639"
SQ   SEQUENCE   780 AA;  88444 MW;  B22967389586D83C CRC64;
     MKKRLPTLLA SLIGSALYSQ QALADLADQC LLGVPAYTKP LVSGDANSLP VHIQADKAAA
     NYPEHALFSG NVYIEQGNST LTADEVQLTQ RQEQNNAPLR TATATGNVNY SSNEIKLQGP
     KAWSNLNTKD TDVYQGNYQI VGRQGRGDAD TMKQRGDNRY TVLENGSFTS CLPGDDSWSV
     VGSEVIHDRE EQVAEIWNAR FKIGKVPVFY SPYLQIPVGD KRRSGFLIPN AKYGSNNGFE
     FSAPYYLNLA PNYDATIMPN YMSKRGTQIQ TEFRYHTTPG EGLVEFDWLP KDRVYSSEHA
     SDGDSDRWLL YWRHNGVMDQ VWRFNVDYTK VSDSNYFDDL DSKYGSTTDG YATQKFSFGY
     ADENWDTALS YKQFQVFDTN SSDAYRTAPQ LDVTYYKNDV GPFDFKVFSQ AAKFTNVNNS
     YPEATRLHIE PTLNLPLANR WGSLNTEAKL MATHYQQENI DEYNENTGTG RHLKGSVNRV
     LPQFKTDGKM VFERDMDYAP DYTQTLEPRL QYLYVPYRNQ NDIGVYDSTI LQTDYSGLFR
     DRTYSGLDRI SSANQLAGGV TTRIYDDQRA ERFNASVGQI YYFSRPRTGD ITGTWDNYDN
     TGSVVWAGDS YWRISNQWGI RGGLQYDSRL NSVALGDAVL EYRRDENRIL QLNYHYASPQ
     YIEQMLSDIS HTGYQQGISQ VGVTGSWQLV DRWSLVGAYY YDTKANQPAD QLVGLQYNTC
     CWAINVGYER KITGWNSTDS SSQYDNKVSF NIELRGLSSN YGLGTDKMLA SGILPYQRAF