ID   LPTD_THIDA              Reviewed;         728 AA.
AC   Q3SGG0;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Tbd_2337;
OS   Thiobacillus denitrificans (strain ATCC 25259).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Thiobacillaceae; Thiobacillus.
OX   NCBI_TaxID=292415;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25259;
RX   PubMed=16452431; DOI=10.1128/jb.188.4.1473-1488.2006;
RA   Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W.,
RA   Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.;
RT   "The genome sequence of the obligately chemolithoautotrophic, facultatively
RT   anaerobic bacterium Thiobacillus denitrificans.";
RL   J. Bacteriol. 188:1473-1488(2006).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000116; AAZ98290.1; -; Genomic_DNA.
DR   RefSeq; WP_011312849.1; NC_007404.1.
DR   AlphaFoldDB; Q3SGG0; -.
DR   SMR; Q3SGG0; -.
DR   STRING; 292415.Tbd_2337; -.
DR   PRIDE; Q3SGG0; -.
DR   EnsemblBacteria; AAZ98290; AAZ98290; Tbd_2337.
DR   KEGG; tbd:Tbd_2337; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000008291; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR045659; LptD_2.
DR   InterPro; IPR007543; LptD_C.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF19838; LptD_2; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           22..728
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_5000103619"
SQ   SEQUENCE   728 AA;  81657 MW;  8029D1EF724B5CF3 CRC64;
     MSALPGFTLA ALLLNVSLAE ANGLVLKKDL ELKGSTVAGK EAPLFLTADR IDSTAVGIIE
     AAGRVEARQA GRNFFADWLR YDTRENSVQA RGKVRLEQPA LLVTGDSLDI DLDTYSGQLA
     APVYRFVGQP GRGDAERIDF IDENNFSLAD ATYTTCSVED EDWYLKIADL DIDRGRDVGT
     AHHASLRFLG VPILYTPWMS FPLGDARKSG ILAPTIGTTE RSGLDIVVPY YLNLAPNYDA
     TLYPRLLSKR GVQLGGEFRY LLEDARGVNR VEYLDDSEAA RTRWSVALNN SYRLNANTQA
     GMLFDRVSDD DYFRDLSNLI SITSLSHLNR EVWVTTQHAH WNAELRAQSF QTLQDSTAST
     PIAEPYARLP HARLGAAQTF GRFEFTLESE ATRFAHPTKT EGTRVLAYPT LRMPLVNDYG
     FLTPQIGWHS TYYALDESAA DDNIVRNLPI FSLDSGVVFD RPMRFSGVDF EQTLEPRVYY
     VYAPYRDQDD IPIFDTGLLD FSYAQMFTPN QFIGGDRIND ANQLTVAVTS RFVEAESGLE
     RLQVTLGQRY YFTPQRVTLP GVDPRSDNTT DLLAAVSGQI TRDWRIDTAW QFDTQNGTVI
     RQNLGASYRP GPGRAINFGY RFIDQTTEQV DVSAQWPLGR RWYGMFRYNY SFQDDKLVEG
     LAGLEYNGGC WALRTVFQRL ATKEDQSTDA LFFQLELNGM GRLGSNPLDV LKQSVPGYRP
     SNEILPTP