ID   LPTD_VIBPA              Reviewed;         781 AA.
AC   Q87ST3;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=VP0339;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000031; BAC58602.1; -; Genomic_DNA.
DR   RefSeq; NP_796718.1; NC_004603.1.
DR   RefSeq; WP_005480552.1; NC_004603.1.
DR   AlphaFoldDB; Q87ST3; -.
DR   SMR; Q87ST3; -.
DR   STRING; 223926.28805322; -.
DR   EnsemblBacteria; BAC58602; BAC58602; BAC58602.
DR   GeneID; 1187806; -.
DR   KEGG; vpa:VP0339; -.
DR   PATRIC; fig|223926.6.peg.326; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..781
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000020293"
SQ   SEQUENCE   781 AA;  89241 MW;  211C7FA791DF5029 CRC64;
     MQHFSRTFIA ASISTALFVP TTQAEANIND SVQEMPATDQ CLVETSGEED ALNTPVVVEA
     DNLQAINGDK AQYSGNVQVT QGPKKITADS VTLHQQDNVV VAEGNVTFND GQVKARSDRV
     TNDINQDTFS LENTEYQFLC QQGRGTAAYI ARTGQSVYEL EDGSITSCPE GDNSWRLVAS
     GIDVDQDEET ATLHHPRFEI MDVPVFYVPY MTMPIGNTRK TGFLFPSLSY GSSDGMEVEV
     PFYWNIAPQY DMTLTALYMQ QRGTKLDTDF RYLTDGWGEG KLKGEYLNSD KKYQDDSRWG
     YQVKHDGIIN KQWIVKVDYS QVSDIDYFLD LDSDIGNRED GQLVQEGHVQ YRSDFWDASL
     TVRDFQILLK EENRPYRLLP QLDLNYYTPL WGDHLNFDVK SQVSRFDTSD TARPNATRVH
     IEPGLTMPLS NSWATWTTEA RVLSTYYSQD LTGLTDVDLK NQLDEQVSRV IPEFRTHAQI
     YLERDTSWVK GYTQTLEPQL QYLYVPEEDQ TNIYNYDTTL LQTDYYGLFR SRKYSGIDKI
     ASANQLSYGA STRFFDDDYK ERLNVSFGQI YYFDKKTKIS NSPNIPDETT NYSSWAVEAD
     FNYNDYLFYH GGVQYDIDLS SMQLANSTLE YQFNGGFIQG NYRYVTREYI EDTIILENLD
     TITRKGISQA GIVAAYEFNR NWSASGQYYY DLNENTDMEW LASLRYQSDC WYIGLTYSNQ
     LLGWENQAIG STGSSPEYEN NFSVNFGIQG FATNQSTGTA VKELDGSDNA IKYGRPFYLN
     N