ID   LPTD_VIBVU              Reviewed;         776 AA.
AC   Q8DED5;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=VV1_0660;
OS   Vibrio vulnificus (strain CMCP6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=216895;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CMCP6;
RA   Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.;
RT   "Complete genome sequence of Vibrio vulnificus CMCP6.";
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; AE016795; AAO09172.1; -; Genomic_DNA.
DR   RefSeq; WP_011078739.1; NC_004459.3.
DR   AlphaFoldDB; Q8DED5; -.
DR   SMR; Q8DED5; -.
DR   EnsemblBacteria; AAO09172; AAO09172; VV1_0660.
DR   KEGG; vvu:VV1_0660; -.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; YDRMPQI; -.
DR   Proteomes; UP000002275; Chromosome 1.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..776
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000020294"
SQ   SEQUENCE   776 AA;  88840 MW;  39602F624548C9EF CRC64;
     MQHFSRTFLA ASIATALFAP YAQAEAILNN SVQEMPTTDQ CLVDAEKNDA NAEIVIQADN
     LQAINGDKAI YSGDVEVTQG NKKITAESVT LHQQENIVVA EGNVTFNDGE VKASSSKVTN
     NMTSETFSLE NTEYQFLCQQ GRGQAAYIAK TGQAVYELED GSITSCPADD NAWRLVASSI
     EVDQNEETAT FYHPRFEVLD VPVFYAPYLT LPIGNTRKTG FLFPSVNYGS SDGLEIEVPF
     YWNIAPNYDL TLTTLYMQQR GVKQDADFRY LSDGWGAGEL KGEYLPGDEK YNDEDRWGYQ
     YKHDGIINKQ WLVSLDYSQV SDIDYFRDLS SDLGNREDGQ LMQQGKVAYR SDFWDMSLQV
     RDFQILLQDN NQPYRLLPQV KFNFYTPLLG NYLNFDVKSE LTQFDIQDAS KPNALRAHVE
     PGLTIPLSTS WATWTTEARL LATYYQQDLD RLTDPTLKSQ LDETVARVIP EYRSHARIYL
     EREAKLFEGY TQSLEPQIQY LYVPEEEQGN IYNYDTTLLQ TDYYGLFRSR KYSSIDKIAA
     ANQLSYGAST RFFDDEYKER LNISFGQIYY IDKKTKLTGN QEETSNYSSW AVETDFNYED
     FLFYHGGIQY DIDLNAMQLA NSTLEYQFTD GFIQGNYRYV TKDYIEDTIS FDELDKITRK
     GISQAGIVGA YNINRHWSAS GQYYYDLTEE IDLEWMASLR YQSDCWYIGF TYTNQLVKWR
     NDVVGGDSNN PVYDTNISVN FGIQGFATKN KAETAAKELD STDNAITYGR PFYLNN