ID   LPTD_VIBVY              Reviewed;         776 AA.
AC   Q7MP83;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=VV0481;
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=196600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016;
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L.,
RA   Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P.,
RA   Lee C.-T., Hor L.-I., Tsai S.-F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine pathogen.";
RL   Genome Res. 13:2577-2587(2003).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; BA000037; BAC93245.1; -; Genomic_DNA.
DR   RefSeq; WP_011149399.1; NC_005139.1.
DR   AlphaFoldDB; Q7MP83; -.
DR   SMR; Q7MP83; -.
DR   STRING; 672.VV93_v1c04480; -.
DR   EnsemblBacteria; BAC93245; BAC93245; BAC93245.
DR   KEGG; vvy:VV0481; -.
DR   PATRIC; fig|196600.6.peg.507; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; YDRMPQI; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000002675; Chromosome I.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..776
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000020295"
SQ   SEQUENCE   776 AA;  88857 MW;  253B11625A6B6F73 CRC64;
     MQHFSRTFLA ASIATALFAP YAQAEAILNN SVQEMPTTDQ CLVDAEKNDA NAEIVIQADN
     LQAINGDKAI YSGDVEVTQG NKKITAESVT LHQQENIVVA EGNVTFNDGE VKASSSKVTN
     NMTSETFSLE NTEYQFLCQQ GRGQAAYIAK TGQAVYELED GSITSCPADD NAWRLVASSI
     EVDQDEETAT FYHPRFEVLD VPVFYAPYLT LPIGNTRKTG FLFPSVNYGS SDGLEIEVPF
     YWNIAPNYDL TLTTLYMQQR GVKQDADFRY LSDGWGSGEL KGEYLPGDEK YNDEDRWGYQ
     YKHDGIINKQ WLVSLDYSQV SDIDYFRDLS SDLGNREDGQ LMQQGKVAYR SDFWDMSLQV
     RDFQILLQDN NQPYRLLPQV KFNFYTPLLG NYLNFDVKSE LTQFDIQDAS KPNALRAHVE
     PGLTIPLSTS WATWTTEARL LATYYQQDLD RLTDPTLKSQ LDETVARVIP EYRSHARIYL
     EREAKLFEGY TQSLEPQIQY LYVPEEEQGN IYNYDTTLLQ TDYYGLFRSR KYSSIDKIAA
     ANQLSYGAST RFFDDEYKER LNISFGQIYY IDKKTKLTGN QEETSNYSSW AVETDFNYED
     FLFYHGGIQY DIDLNAMQLA NSTLEYQFTD GFIQGNYRYV TKDYIEDTIS FDELDKITRK
     GISQAGIVGA YNINRHWSAS GQYYYDLTEE IDLEWMASLR YQSDCWYIGF TYTNQLVKWR
     NDVVGGDSNN PVYDTNISVN FGIQGFATKN KAETAAKELD STDNAITYGR PFYLNN