LPTD_YERPA
ID LPTD_YERPA Reviewed; 780 AA.
AC Q1C0H2;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 2.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN OrderedLocusNames=YPA_4089;
OS Yersinia pestis bv. Antiqua (strain Antiqua).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=360102;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Antiqua;
RX PubMed=16740952; DOI=10.1128/jb.00124-06;
RA Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA Worsham P., Chu M.C., Andersen G.L.;
RT "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT evidence of gene reduction in an emerging pathogen.";
RL J. Bacteriol. 188:4453-4463(2006).
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000255|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABG16050.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000308; ABG16050.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_002228111.1; NZ_CP009906.1.
DR AlphaFoldDB; Q1C0H2; -.
DR SMR; Q1C0H2; -.
DR EnsemblBacteria; ABG16050; ABG16050; YPA_4089.
DR GeneID; 57974115; -.
DR KEGG; ypa:YPA_4089; -.
DR Proteomes; UP000001971; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT CHAIN 25..780
FT /note="LPS-assembly protein LptD"
FT /id="PRO_5000116369"
SQ SEQUENCE 780 AA; 87909 MW; D4C3706260D2937A CRC64;
MKKRFPTLLA TLIWTALYSQ HTLADLAEQC MLGVPTYDQP LVTGDPNQLP VRINADKTEA
NYPDNALFTG NVIVQQGNST LTANQVELTQ VQKPGEVIPL RTVTATGDVN YDDPQIKLKG
PKGWSNLNTK DTDMDKGKYQ MVGRQGRGDA DLMKLRDQSR YTILKNGTFT SCLPGDNSWS
VVGSEVIHDR EEQVVEVWNA RFKIGKVPVF YSPYMQLPVG DKRRSGFLIP NAKFTSNNGF
EFLLPYYWNI APNFDATITP HYMERRGLQW QNEFRYLLAP GSGTMALDWL PNDRIYTGPD
GTDKNATRWL YYWGHSGVMD QVWRFNINYT RVSDPAYFTD LTSQYGSTTD GYATQIFTAG
YANENWNATL SSKQFQVFTA AGNSNAYRAQ PQLDMNYYKN DVGPFDMHVY GQAAKFTSVN
PTNPEASRFH IEPTVNLPLS NSWGSINTEA KLLATHYQQD IPASFADNAS NPKLKDSVNR
VLPQFKVDGK VVFDRSMDWA TGFTQTLEPR AQYLYVPYRN QDDIYIYDTT LMQSDYSGLF
RDRTYSGLDR IASANQVSTG LTSRIYDDAR VERFNVSVGQ IYYFSRSRTG NTEAIDNSNA
TGSLVWAGDT FWRINDQLGL KGGAQYDTRL GSLTLGNAIM EYRKDADRMI QLNYRYASPK
YIQAAVPKVY NPDYQQGISQ VGTTASWPIA DRWAIVGAYY YDTKAKQPAS QLVGLQYNTC
CWAVNLGYER KITGWNAQGQ TSKYDNKIGF NIELRGLSGG HSLGTAQMLN SGILPYQSAF