ID   LPTD_YERPS              Reviewed;         780 AA.
AC   Q66EQ6;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=YPTB0636;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; BX936398; CAH19876.1; -; Genomic_DNA.
DR   RefSeq; WP_011191712.1; NZ_CP009712.1.
DR   AlphaFoldDB; Q66EQ6; -.
DR   SMR; Q66EQ6; -.
DR   EnsemblBacteria; CAH19876; CAH19876; YPTB0636.
DR   GeneID; 66842943; -.
DR   KEGG; yps:YPTB0636; -.
DR   OMA; DYSHLDW; -.
DR   Proteomes; UP000001011; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..780
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000020302"
SQ   SEQUENCE   780 AA;  87963 MW;  19DDE1CE629F877E CRC64;
     MKKRFPTLLA TLIWTALYSQ HTLADLAEQC MLGVPTYDQP LVTGDPNQLP VRINADKTEA
     NYPDNALFTG NVIVQQGNST LTANQVELTQ VQKPGEVIPL RTVTATGDVN YDDPQIKLKG
     PKGWSNLNTK DTDIDKGKYQ MVGRQGRGDA DLMKLRDQSR YTILKNGTFT SCLPGDNSWS
     VVGSEVIHDR EEQVVEVWNA RFKIGKVPVF YSPYMQLPVG DKRRSGFLIP NAKFTSNNGF
     EFLLPYYWNI APNFDATITP HYMERRGLQW QNEFRYLLAP GSGTMALDWL PNDRIYTGPD
     GTDKNATRWL YYWGHSGVMD QVWRFNINYT RVSDPAYFTD LTSQYGSTTD GYATQIFTAG
     YANENWNATL SSKQFQVFTA AGNSNAYRAQ PQLDMNYYKN DVGPFDMHVY GQAAKFTSVN
     PTNPEASRFH IEPTVNLPLS NSWGSINTEA KLLATHYQQD IPASFADNAS NPKLKDSVNR
     VLPQFKVDGK VVFDRSMDWA TGFTQTLEPR AQYLYVPYRN QDDIYIYDTT LMQSDYSGLF
     RDRTYSGLDR IASANQVSTG LTSRIYDDAR VERFNVSVGQ IYYFSRSRTG NTEAIDNSND
     TGSLVWAGDT FWRINDQLGL KGGAQYDTRL GSLTLGNAIM EYRRDADRMI QLNYRYASPK
     YIQAAVPKVY NPDYQQGISQ VGTTASWPIA DRWAIVGAYY YDTKAKQPAS QLVGLQYNTC
     CWAVNLGYER KITGWNAQGQ TSKYDNKIGF NIELRGLSGG HSLGTAQMLN SGILPYQSAF