ID   LPTE_SALTY              Reviewed;         196 AA.
AC   Q8ZQZ7;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=LPS-assembly lipoprotein LptE {ECO:0000255|HAMAP-Rule:MF_01186};
DE   Flags: Precursor;
GN   Name=lptE {ECO:0000255|HAMAP-Rule:MF_01186}; Synonyms=rlpB;
GN   OrderedLocusNames=STM0647;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Together with LptD, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane. Required
CC       for the proper assembly of LptD. Binds LPS and may serve as the LPS
CC       recognition site at the outer membrane. {ECO:0000255|HAMAP-
CC       Rule:MF_01186}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptD. {ECO:0000255|HAMAP-Rule:MF_01186}.
CC   -!- INTERACTION:
CC       Q8ZQZ7; Q8ZRW0: lptD; NbExp=3; IntAct=EBI-16111540, EBI-16111554;
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01186}; Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_01186}.
CC   -!- SIMILARITY: Belongs to the LptE lipoprotein family. {ECO:0000255|HAMAP-
CC       Rule:MF_01186}.
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DR   EMBL; AE006468; AAL19598.1; -; Genomic_DNA.
DR   RefSeq; NP_459639.1; NC_003197.2.
DR   RefSeq; WP_001269947.1; NC_003197.2.
DR   PDB; 4N4R; X-ray; 2.80 A; B/D=1-196.
DR   PDBsum; 4N4R; -.
DR   AlphaFoldDB; Q8ZQZ7; -.
DR   SMR; Q8ZQZ7; -.
DR   DIP; DIP-61033N; -.
DR   IntAct; Q8ZQZ7; 1.
DR   STRING; 99287.STM0647; -.
DR   PaxDb; Q8ZQZ7; -.
DR   DNASU; 1252167; -.
DR   EnsemblBacteria; AAL19598; AAL19598; STM0647.
DR   GeneID; 1252167; -.
DR   KEGG; stm:STM0647; -.
DR   PATRIC; fig|99287.12.peg.683; -.
DR   HOGENOM; CLU_103309_1_1_6; -.
DR   OMA; TTVNRNY; -.
DR   PhylomeDB; Q8ZQZ7; -.
DR   BioCyc; SENT99287:STM0647-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IBA:GO_Central.
DR   GO; GO:0001530; F:lipopolysaccharide binding; IBA:GO_Central.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IBA:GO_Central.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IBA:GO_Central.
DR   HAMAP; MF_01186; LPS_assembly_LptE; 1.
DR   InterPro; IPR007485; LPS_assembly_LptE.
DR   PANTHER; PTHR38098; PTHR38098; 1.
DR   Pfam; PF04390; LptE; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01186"
FT   CHAIN           19..196
FT                   /note="LPS-assembly lipoprotein LptE"
FT                   /id="PRO_0000281184"
FT   REGION          171..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           19
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01186"
FT   LIPID           19
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01186"
FT   HELIX           31..33
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   STRAND          34..39
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   HELIX           46..57
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   STRAND          61..63
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   STRAND          74..89
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   STRAND          95..109
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   STRAND          115..127
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   HELIX           130..132
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   HELIX           133..157
FT                   /evidence="ECO:0007829|PDB:4N4R"
FT   HELIX           159..167
FT                   /evidence="ECO:0007829|PDB:4N4R"
SQ   SEQUENCE   196 AA;  21458 MW;  0277352CF72BF8E5 CRC64;
     MRYLVTLLLS LAVLVTAGCG WHLRSTTQVP ASMKTMILDS GDPNGPLSRA VRNQLRLNNV
     NLLDKDTTRK DVPSLRLGTV TILQDTASVF QDGQTAEYQM VMTVNASVLI PGHDIYPIST
     KVYRSFFDNP QMALAKDNEQ AMIVQEMYDK AAEQLIRKLT SVRAADIQAT KEEATADNET
     AAPASTPARV STTLSN