LPW_CORGL
ID LPW_CORGL Reviewed; 17 AA.
AC P06556; Q45304;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1988, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=trp operon leader peptide;
GN Name=trpL; OrderedLocusNames=Cgl3028.1, cg3357.1;
OS Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS JCM 1318 / LMG 3730 / NCIMB 10025).
OC Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC Corynebacterium.
OX NCBI_TaxID=196627;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3808947; DOI=10.1093/nar/14.24.10113;
RA Matsui K., Sano K., Ohtsubo E.;
RT "Complete nucleotide and deduced amino acid sequences of the Brevibacterium
RT lactofermentum tryptophan operon.";
RL Nucleic Acids Res. 14:10113-10114(1986).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3667535; DOI=10.1128/jb.169.11.5330-5332.1987;
RA Matsui K., Miwa K., Sano K.;
RT "Two single-base-pair substitutions causing desensitization to tryptophan
RT feedback inhibition of anthranilate synthase and enhanced expression of
RT tryptophan genes of Brevibacterium lactofermentum.";
RL J. Bacteriol. 169:5330-5332(1987).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=AJ12036;
RX PubMed=3609747; DOI=10.1016/0378-1119(87)90007-2;
RA Sano K., Matsui K.;
RT "Structure and function of the trp operon control regions of Brevibacterium
RT lactofermentum, a glutamic-acid-producing bacterium.";
RL Gene 53:191-200(1987).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 13059 / LMG 3658 / NCIB 10332 / AS019 / 613;
RX PubMed=2263476; DOI=10.1093/nar/18.23.7138;
RA Heery D.M., Dunican L.K.;
RT "Nucleotide sequence of the Corynebacterium glutamicum trpE gene.";
RL Nucleic Acids Res. 18:7138-7138(1990).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC 10025;
RX PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA Ikeda M., Nakagawa S.;
RT "The Corynebacterium glutamicum genome: features and impacts on
RT biotechnological processes.";
RL Appl. Microbiol. Biotechnol. 62:99-109(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC 10025;
RX PubMed=12948626; DOI=10.1016/s0168-1656(03)00154-8;
RA Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A.,
RA Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A.,
RA Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F.,
RA Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O.,
RA Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
RT "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its
RT impact on the production of L-aspartate-derived amino acids and vitamins.";
RL J. Biotechnol. 104:5-25(2003).
RN [7]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-13.
RC STRAIN=ATCC 21850;
RX PubMed=7683184; DOI=10.1128/aem.59.3.791-799.1993;
RA Herry D.M., Dunican L.K.;
RT "Cloning of the trp gene cluster from a tryptophan-hyperproducing strain of
RT Corynebacterium glutamicum: identification of a mutation in the trp leader
RT sequence.";
RL Appl. Environ. Microbiol. 59:791-799(1993).
CC -!- FUNCTION: This protein is involved in control of the biosynthesis of
CC tryptophan.
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DR EMBL; X04960; CAA28622.1; -; Genomic_DNA.
DR EMBL; M17892; AAB59110.1; -; Genomic_DNA.
DR EMBL; M16663; AAA83988.1; -; Genomic_DNA.
DR EMBL; X55994; CAA39466.1; -; Genomic_DNA.
DR EMBL; BA000036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BX927157; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; A29834; A29834.
DR AlphaFoldDB; P06556; -.
DR Proteomes; UP000000582; Chromosome.
DR GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-KW.
PE 4: Predicted;
KW Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Leader peptide;
KW Reference proteome; Tryptophan biosynthesis.
FT PEPTIDE 1..17
FT /note="trp operon leader peptide"
FT /id="PRO_0000044022"
FT CONFLICT 16
FT /note="A -> G (in Ref. 3; AAA83988)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 17 AA; 2112 MW; 74C7E7924DAAE56B CRC64;
MNNSCLSQST QWWWRAN