ID   LR2BP_MACFA             Reviewed;         348 AA.
AC   Q4R3N2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=LRP2-binding protein;
GN   Name=LRP2BP; ORFNames=QtsA-15783;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May act as an adapter that regulates LRP2 function.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with LRP2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Detected in a
CC       vesicular staining pattern close to the plasma membrane and throughout
CC       the cytoplasm. {ECO:0000250}.
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DR   EMBL; AB179234; BAE02285.1; -; mRNA.
DR   RefSeq; NP_001272201.1; NM_001285272.1.
DR   AlphaFoldDB; Q4R3N2; -.
DR   SMR; Q4R3N2; -.
DR   STRING; 9541.XP_005556478.1; -.
DR   PRIDE; Q4R3N2; -.
DR   GeneID; 101925871; -.
DR   CTD; 55805; -.
DR   eggNOG; KOG1550; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR006597; Sel1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF08238; Sel1; 5.
DR   SMART; SM00671; SEL1; 5.
DR   PROSITE; PS50005; TPR; 1.
DR   PROSITE; PS50293; TPR_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Repeat; TPR repeat.
FT   CHAIN           1..348
FT                   /note="LRP2-binding protein"
FT                   /id="PRO_0000315708"
FT   REPEAT          60..93
FT                   /note="TPR"
FT   REPEAT          94..126
FT                   /note="Sel1-like 1"
FT   REPEAT          134..169
FT                   /note="Sel1-like 2"
FT   REPEAT          174..207
FT                   /note="Sel1-like 3"
FT   REPEAT          208..243
FT                   /note="Sel1-like 4"
FT   REPEAT          244..278
FT                   /note="Sel1-like 5"
FT   REPEAT          298..333
FT                   /note="Sel1-like 6"
SQ   SEQUENCE   348 AA;  39948 MW;  077DA1DBA3A8A146 CRC64;
     MKLTSEKLPK NPFYASISQY AAKNQKSFQW EKEKTDHYSH ANLVDKALQL LKKRILKGDT
     LAYFLRGQLY FEEGWYEEAL EQFEEIEEKD HQATYQLGVM YYDGLGTILN SEKGVDYMKK
     ILDSPCPKAR HLKFAAAYNL GRAYYEGKGV KRSNEEAERL WLFAADNGNP KASVKAQSML
     GLYYSTKEPK ELEKAFYWHS EACGNGNLES QGALGLMYLY GQGIRQDTEA ALHCLREAAE
     RGNVYAQGNL VEYYYKMKFF TKCVAFSKRI ADYDEVHDIP MIAQVTDCLP EFISRGMAMA
     SFYHARCLQL GLGITRDEAT AKHYYSKACR LNPALADELR SLLIRQRI