LR2BP_XENLA
ID LR2BP_XENLA Reviewed; 341 AA.
AC Q6IND7;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=LRP2-binding protein;
GN Name=lrp2bp;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Oocyte;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May act as an adapter that regulates LRP2 function.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR EMBL; BC072346; AAH72346.1; -; mRNA.
DR RefSeq; NP_001085144.1; NM_001091675.1.
DR AlphaFoldDB; Q6IND7; -.
DR SMR; Q6IND7; -.
DR DNASU; 432223; -.
DR GeneID; 432223; -.
DR KEGG; xla:432223; -.
DR CTD; 432223; -.
DR Xenbase; XB-GENE-6078212; lrp2bp.S.
DR OrthoDB; 1039341at2759; -.
DR Proteomes; UP000186698; Chromosome 1S.
DR Bgee; 432223; Expressed in testis and 11 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR006597; Sel1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF08238; Sel1; 5.
DR SMART; SM00671; SEL1; 6.
PE 2: Evidence at transcript level;
KW Cytoplasm; Reference proteome; Repeat; TPR repeat.
FT CHAIN 1..341
FT /note="LRP2-binding protein"
FT /id="PRO_0000315712"
FT REPEAT 56..89
FT /note="TPR"
FT REPEAT 90..122
FT /note="Sel1-like 1"
FT REPEAT 130..165
FT /note="Sel1-like 2"
FT REPEAT 170..203
FT /note="Sel1-like 3"
FT REPEAT 204..239
FT /note="Sel1-like 4"
FT REPEAT 240..271
FT /note="Sel1-like 5"
FT REPEAT 291..326
FT /note="Sel1-like 6"
SQ SEQUENCE 341 AA; 38220 MW; 91C05DC7AC8B0AFC CRC64;
MKLRSECLPK SEHGTVLYTL SQLPDFPPCK DQDYSHEDLL QTAETFLKSR IKEGDVQANF
LLGQLFFEEG WYEDALLQFE KVKDEDNQAL YQAGVMYYDG LGTQEDHRKG VKYMERIVTS
DCPSAKHLKY AAAYNLGRAY FEGYGIPHSD KEAERWWLFA ADNGNPKASL KAQSVLGMYY
SSPPNVDLQK AFLWHSEACG NGSLESQGAL GVMYLYGNGI KKNVQAAIEC LKEAAERGNV
YAQGHLVSCY YQRKLYTKAV ELAKKIVSHD NIELLVNTTD CLPSYTVKGV AIATFYFARC
LHLGLGIKQD STAAKQLYSK AAQLDAQVAA ELNFDIIYGK I