LRAT1_MOUSE
ID LRAT1_MOUSE Reviewed; 292 AA.
AC Q9D650; Q99K34;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=Protein LRATD1 {ECO:0000305};
DE AltName: Full=LRAT domain-containing 1;
DE AltName: Full=Protein FAM84A;
GN Name=Lratd1 {ECO:0000305}; Synonyms=Fam84a {ECO:0000312|MGI:MGI:2145011};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Skin;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May play a role in cell morphology and motility.
CC {ECO:0000250|UniProtKB:Q96KN4}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96KN4}.
CC -!- SIMILARITY: Belongs to the LRATD family. {ECO:0000305}.
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DR EMBL; AK014625; BAB29470.1; -; mRNA.
DR EMBL; BC005488; AAH05488.1; -; mRNA.
DR CCDS; CCDS25820.1; -.
DR RefSeq; NP_083283.2; NM_029007.2.
DR AlphaFoldDB; Q9D650; -.
DR SMR; Q9D650; -.
DR STRING; 10090.ENSMUSP00000020926; -.
DR iPTMnet; Q9D650; -.
DR PhosphoSitePlus; Q9D650; -.
DR MaxQB; Q9D650; -.
DR PaxDb; Q9D650; -.
DR PRIDE; Q9D650; -.
DR ProteomicsDB; 266834; -.
DR DNASU; 105005; -.
DR GeneID; 105005; -.
DR KEGG; mmu:105005; -.
DR UCSC; uc007nbn.1; mouse.
DR CTD; 151354; -.
DR MGI; MGI:2145011; Lratd1.
DR eggNOG; ENOG502QPSG; Eukaryota.
DR InParanoid; Q9D650; -.
DR OrthoDB; 953643at2759; -.
DR PhylomeDB; Q9D650; -.
DR TreeFam; TF330836; -.
DR BioGRID-ORCS; 105005; 3 hits in 75 CRISPR screens.
DR PRO; PR:Q9D650; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; Q9D650; protein.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000902; P:cell morphogenesis; ISS:UniProtKB.
DR GO; GO:0048870; P:cell motility; ISS:UniProtKB.
DR InterPro; IPR007053; LRAT_dom.
DR InterPro; IPR043299; LRATD1_LRATD2.
DR PANTHER; PTHR46341; PTHR46341; 1.
DR PROSITE; PS51934; LRAT; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Phosphoprotein; Reference proteome.
FT CHAIN 1..292
FT /note="Protein LRATD1"
FT /id="PRO_0000234426"
FT DOMAIN 133..228
FT /note="LRAT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01283"
FT MOD_RES 38
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96KN4"
FT CONFLICT 153
FT /note="V -> I (in Ref. 2; AAH05488)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 292 AA; 32676 MW; D500C38DC50AFAFA CRC64;
MGNQLDRITH LNYSELPTGD PSGIEKDELR VGVAYFFSDE EEDLDERGQP DKFGVKGPPG
CSPCPESPSR HHHHLLHQLV LNETQFSAFR GQECIFSKVT GGPQGADLSV YAVTALPAIC
EPGDLLELLW LQPATEQPAP APHWAVYVGG GQVIHLHQGE IRQDSLYQAG AANVGRVVNS
WYRYRPLVAE LVVQNACGHL GLKSEEICWT NSESFAAWCR FGKREFKAGG EVPAGTQPPQ
QQYYLKVHLE ENKVHTARFH SLEDLIREKR RIDASGRLRV LQELEDFVDD KE
