ID   LRC10_BOVIN             Reviewed;         278 AA.
AC   Q24K06;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Leucine-rich repeat-containing protein 10;
GN   Name=LRRC10;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Heart ventricle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play important roles in cardiac development and/or
CC       cardiac function. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC114091; AAI14092.1; -; mRNA.
DR   RefSeq; NP_001069225.1; NM_001075757.2.
DR   AlphaFoldDB; Q24K06; -.
DR   SMR; Q24K06; -.
DR   STRING; 9913.ENSBTAP00000025497; -.
DR   PaxDb; Q24K06; -.
DR   Ensembl; ENSBTAT00000025497; ENSBTAP00000025497; ENSBTAG00000019157.
DR   GeneID; 517750; -.
DR   KEGG; bta:517750; -.
DR   CTD; 376132; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019157; -.
DR   VGNC; VGNC:52796; LRRC10.
DR   eggNOG; KOG0619; Eukaryota.
DR   GeneTree; ENSGT00940000155040; -.
DR   HOGENOM; CLU_000288_18_15_1; -.
DR   InParanoid; Q24K06; -.
DR   OMA; RNSIRYF; -.
DR   OrthoDB; 987531at2759; -.
DR   TreeFam; TF332853; -.
DR   Proteomes; UP000009136; Chromosome 5.
DR   Bgee; ENSBTAG00000019157; Expressed in cardiac ventricle and 14 other tissues.
DR   GO; GO:0005856; C:cytoskeleton; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030017; C:sarcomere; IBA:GO_Central.
DR   GO; GO:0003779; F:actin binding; IBA:GO_Central.
DR   GO; GO:0051393; F:alpha-actinin binding; IEA:Ensembl.
DR   GO; GO:0055013; P:cardiac muscle cell development; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00369; LRR_TYP; 5.
DR   PROSITE; PS51450; LRR; 7.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..278
FT                   /note="Leucine-rich repeat-containing protein 10"
FT                   /id="PRO_0000346161"
FT   REPEAT          30..51
FT                   /note="LRR 1"
FT   REPEAT          52..74
FT                   /note="LRR 2"
FT   REPEAT          76..97
FT                   /note="LRR 3"
FT   REPEAT          98..121
FT                   /note="LRR 4"
FT   REPEAT          123..143
FT                   /note="LRR 5"
FT   REPEAT          144..166
FT                   /note="LRR 6"
FT   REPEAT          167..189
FT                   /note="LRR 7"
FT   REPEAT          191..213
FT                   /note="LRR 8"
FT   REGION          239..278
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..260
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   278 AA;  31760 MW;  8D7EF12600078D51 CRC64;
     MGNTIRAFVA FIPADRCQNY VARDLREMPL DRMVDLSGSQ LRRFPVHVCS FQELVKLYLS
     DNRLNSLPPE LGQLQNLQIL ALDFNNFKAL PQVVCTLKQL CILYLGNNKL CDLPRELSLL
     QNLRTLWVEA NYLTKLPEVV CELSLLKTLH AGSNALRLLP GQLQRLRELR TIWLSGNLLT
     DFPPVLLHMP FLEIIDVDRN SIRYFPSLAH LSSLKLVIYD HNPCRNAPKV AKGVRRVGRW
     AEETPEPDPR KARRYALARE ESQEAQLPAL PPLPPTNS