ID   LRC14_XENLA             Reviewed;         509 AA.
AC   Q640Z9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Leucine-rich repeat-containing protein 14 {ECO:0000250|UniProtKB:Q15048};
GN   Name=lrrc14 {ECO:0000250|UniProtKB:Q15048};
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q15048}.
CC   -!- SIMILARITY: Belongs to the PRAME family. LRRC14 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; BC082440; AAH82440.1; -; mRNA.
DR   RefSeq; NP_001087894.1; NM_001094425.1.
DR   AlphaFoldDB; Q640Z9; -.
DR   SMR; Q640Z9; -.
DR   DNASU; 447755; -.
DR   GeneID; 447755; -.
DR   KEGG; xla:447755; -.
DR   CTD; 447755; -.
DR   Xenbase; XB-GENE-5844993; lrrc14.L.
DR   OrthoDB; 563553at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 447755; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR026292; LRRC14.
DR   PANTHER; PTHR14224:SF9; PTHR14224:SF9; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   PROSITE; PS51450; LRR; 3.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..509
FT                   /note="Leucine-rich repeat-containing protein 14"
FT                   /id="PRO_0000344243"
FT   REPEAT          111..146
FT                   /note="LRR 1; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          210..234
FT                   /note="LRR 2; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          235..262
FT                   /note="LRR 3; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          263..298
FT                   /note="LRR 4; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          299..323
FT                   /note="LRR 5"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          324..355
FT                   /note="LRR 6"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          356..374
FT                   /note="LRR 7"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          380..407
FT                   /note="LRR 8"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          408..432
FT                   /note="LRR 9"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
SQ   SEQUENCE   509 AA;  57060 MW;  7B281504A5F1B39B CRC64;
     MESLVSVCAQ KLVCDHSSLR RALDLMPKEL YPALFKAAFL GKKTLVLQDL VQTWPFAVLS
     FHKLLNSNRH CDPQLATEKP SKLCVQTVIL GVITYLSDAL TKGPEGPQAG RQRLRLLDMT
     GMQEEGLEQN PDTMSLWSRT VTLAKACIDV SKRHSEEVMQ VSKRRRSCHI NALPASSPLY
     IEVRVDLFVN STSYGVLREA LLVSSHSPLR LQCRDFRAEE LSLRSTAGLL ELLNPGSVRQ
     IDLRFNNLGL SGLNVLLPHM AKFSHLQSLK LPYSNVDVRR LSPVMEEGLQ SFASQLGQLG
     ALKELNLGSS RLSGRLRQLL GGLQRPLESL ELAFCSLLPM DLSYLSQSSH MSSLRKLDLS
     GNNLSEFLLT PFLHLLAEIS GHLLYLDVME CKLADAHLSA LMPILCRCSW LRYLGLFCNP
     ISSDGLRMVL QNLVRLPELH LVVYPFPVDC YSDPTHFSST AASLDSSFDH EKLTRVGEEL
     QQMLVRAQRM DMVWTTDMYV QRTLDSLSL