LRC30_MOUSE
ID LRC30_MOUSE Reviewed; 300 AA.
AC Q3UV48;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Leucine-rich repeat-containing protein 30;
GN Name=Lrrc30;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Bone;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
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DR EMBL; AK137598; BAE23425.1; -; mRNA.
DR CCDS; CCDS28949.1; -.
DR RefSeq; NP_001028512.2; NM_001033340.3.
DR AlphaFoldDB; Q3UV48; -.
DR SMR; Q3UV48; -.
DR STRING; 10090.ENSMUSP00000094893; -.
DR iPTMnet; Q3UV48; -.
DR PhosphoSitePlus; Q3UV48; -.
DR PaxDb; Q3UV48; -.
DR PRIDE; Q3UV48; -.
DR ProteomicsDB; 287267; -.
DR GeneID; 240131; -.
DR KEGG; mmu:240131; -.
DR CTD; 339291; -.
DR MGI; MGI:2685172; Lrrc30.
DR eggNOG; KOG0619; Eukaryota.
DR InParanoid; Q3UV48; -.
DR OrthoDB; 484111at2759; -.
DR PhylomeDB; Q3UV48; -.
DR BioGRID-ORCS; 240131; 1 hit in 72 CRISPR screens.
DR PRO; PR:Q3UV48; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; Q3UV48; protein.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00369; LRR_TYP; 5.
DR PROSITE; PS51450; LRR; 8.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..300
FT /note="Leucine-rich repeat-containing protein 30"
FT /id="PRO_0000310987"
FT REPEAT 47..69
FT /note="LRR 1"
FT REPEAT 70..92
FT /note="LRR 2"
FT REPEAT 94..115
FT /note="LRR 3"
FT REPEAT 116..138
FT /note="LRR 4"
FT REPEAT 139..161
FT /note="LRR 5"
FT REPEAT 162..184
FT /note="LRR 6"
FT REPEAT 186..207
FT /note="LRR 7"
FT REPEAT 209..230
FT /note="LRR 8"
FT REPEAT 231..253
FT /note="LRR 9"
FT REPEAT 261..286
FT /note="LRR 10"
SQ SEQUENCE 300 AA; 33931 MW; 891936A8EE2065F9 CRC64;
MGTKQSRASS NDKDPKRLLL GKRQKFSSWD DTLLLGKDPR SLLKRGMRHV SFSLVTKGMT
DIPDFLWGLL EVQKLNLSHN QLRVLPPEVG RLTRIVVLNL CGNCLKSLPR EVSLLQSLKV
LFLNMNCLAE VPAELSLCRN LEVLSMSHNC LSQLPASFAD LSRLRKLNLS NNYFAHIPLC
VFSLKELDFL HVGSNRLKNI AESIQCLASL QIFIAESNNI HSFPRSLCLV TSLELLNLNN
NDIQTLPDEL YLLCRLGRIA WNPMDKGLHI SHNPLSKPLP ELVEGGLEML YSYLKDKKHN
