ID   LRC40_XENTR             Reviewed;         605 AA.
AC   Q5M8G4;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Leucine-rich repeat-containing protein 40;
GN   Name=lrrc40;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC088034; AAH88034.1; -; mRNA.
DR   RefSeq; NP_001011310.1; NM_001011310.1.
DR   AlphaFoldDB; Q5M8G4; -.
DR   SMR; Q5M8G4; -.
DR   STRING; 8364.ENSXETP00000050945; -.
DR   PaxDb; Q5M8G4; -.
DR   GeneID; 496765; -.
DR   KEGG; xtr:496765; -.
DR   CTD; 55631; -.
DR   Xenbase; XB-GENE-968689; lrrc40.
DR   eggNOG; KOG0472; Eukaryota.
DR   HOGENOM; CLU_000288_18_23_1; -.
DR   InParanoid; Q5M8G4; -.
DR   OMA; HNAIPSI; -.
DR   OrthoDB; 826997at2759; -.
DR   PhylomeDB; Q5M8G4; -.
DR   TreeFam; TF354310; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IBA:GO_Central.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 4.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13855; LRR_8; 4.
DR   SMART; SM00369; LRR_TYP; 13.
DR   PROSITE; PS51450; LRR; 17.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..605
FT                   /note="Leucine-rich repeat-containing protein 40"
FT                   /id="PRO_0000226263"
FT   REPEAT          83..104
FT                   /note="LRR 1"
FT   REPEAT          106..127
FT                   /note="LRR 2"
FT   REPEAT          129..151
FT                   /note="LRR 3"
FT   REPEAT          152..173
FT                   /note="LRR 4"
FT   REPEAT          175..196
FT                   /note="LRR 5"
FT   REPEAT          198..219
FT                   /note="LRR 6"
FT   REPEAT          221..242
FT                   /note="LRR 7"
FT   REPEAT          244..265
FT                   /note="LRR 8"
FT   REPEAT          266..287
FT                   /note="LRR 9"
FT   REPEAT          290..311
FT                   /note="LRR 10"
FT   REPEAT          313..335
FT                   /note="LRR 11"
FT   REPEAT          336..357
FT                   /note="LRR 12"
FT   REPEAT          429..450
FT                   /note="LRR 13"
FT   REPEAT          453..475
FT                   /note="LRR 14"
FT   REPEAT          476..497
FT                   /note="LRR 15"
FT   REPEAT          499..520
FT                   /note="LRR 16"
FT   REPEAT          522..543
FT                   /note="LRR 17"
FT   REPEAT          546..567
FT                   /note="LRR 18"
FT   REPEAT          569..590
FT                   /note="LRR 19"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  67188 MW;  26825EF51A404D6F CRC64;
     MSRFRRGGKA PDPLSGFRAP KEQEPAVPHG LIKAARKSGQ LNLSARGLTD VPVSVWRINV
     DTPPEAHQNV DFGGSDRWWE QTDLTKLILA SNKLQLLSED ISLLPALVVL DIHDNQIVSL
     PCAIKELTNL QKLNISHNKI KQLPKELQHL QNLKSLLLQH NQLEELPDSI GHLSILEELD
     VSNNCLRSIS SSVGQLTGLV KFNLSSNKLT ALPTEIGKMK NLKQLDCTSN LLENVPASVA
     GMESLEQLYL RQNKLTYLPE LPFLTKLKEL HVGNNQIQTL GPEHLQNLSS LSVLELRYNK
     LKVLPEEISL LNGLERLDLS NNDLGSLPCT LGSLPNLKSL QLEGNPLRGI RRDILNKGTQ
     ELLKYLKGRV QVPDVKTQED ENSTATAMTL PSESVVNTHA IVTLKTLEYC EKQASLIPEA
     VFNATGSSFI TTVNFSKNQL TEVPARIVEM KDSVCDVNLG FNKISSISLN LCMLLKLTHI
     DMRNNVLTSL PSEMEAMTRL QSVILSFNRF KHFPDVLYRI PTLETILISS NQIGSIDPTQ
     LIKMTKLSTL DLQNNDLLQI PPALGNCESL RALHLEGNPF RNPRAAILAK GTVAVLEYLR
     SRIPT