ID   LRC42_BOVIN             Reviewed;         428 AA.
AC   Q2HJ90;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Leucine-rich repeat-containing protein 42;
GN   Name=LRRC42;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Uterus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LRRC42 family. {ECO:0000305}.
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DR   EMBL; BC113249; AAI13250.1; -; mRNA.
DR   RefSeq; NP_001039851.1; NM_001046386.1.
DR   AlphaFoldDB; Q2HJ90; -.
DR   STRING; 9913.ENSBTAP00000040839; -.
DR   PaxDb; Q2HJ90; -.
DR   PRIDE; Q2HJ90; -.
DR   Ensembl; ENSBTAT00000043252; ENSBTAP00000040839; ENSBTAG00000019198.
DR   GeneID; 534728; -.
DR   KEGG; bta:534728; -.
DR   CTD; 115353; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019198; -.
DR   VGNC; VGNC:31016; LRRC42.
DR   eggNOG; ENOG502QQJZ; Eukaryota.
DR   GeneTree; ENSGT00390000002727; -.
DR   HOGENOM; CLU_053705_0_0_1; -.
DR   InParanoid; Q2HJ90; -.
DR   OMA; QMPKQKK; -.
DR   OrthoDB; 1204825at2759; -.
DR   TreeFam; TF331102; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000019198; Expressed in oocyte and 105 other tissues.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR039631; LRRC42.
DR   PANTHER; PTHR31994; PTHR31994; 1.
DR   Pfam; PF13516; LRR_6; 3.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Phosphoprotein; Reference proteome; Repeat.
FT   CHAIN           1..428
FT                   /note="Leucine-rich repeat-containing protein 42"
FT                   /id="PRO_0000360040"
FT   REPEAT          149..170
FT                   /note="LRR 1"
FT   REPEAT          174..195
FT                   /note="LRR 2"
FT   REPEAT          202..222
FT                   /note="LRR 3"
FT   REPEAT          234..255
FT                   /note="LRR 4"
FT   REPEAT          259..280
FT                   /note="LRR 5"
FT   REGION          379..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        383..401
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         406
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8R2U7"
FT   MOD_RES         407
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y546"
SQ   SEQUENCE   428 AA;  48585 MW;  1C03D8409462CF5C CRC64;
     MSYYLNSENH LDSGPIYVRE NGQLHMVNLA LDDVRSSLQK PRPFRLFPKG FSVELCMNRE
     DDTAQKEKTD HFIFTYTREG NLRYSAKSLF SLVLGFISDN VDHIDSLIGF PEQIAEKLFS
     AAEARQKFTE PGAGLRALQK FTEAYGSLVL CSLCLRNRYL VISEKLEEIK SFRELTCLDL
     SCCKLGDEHE LLEHLTNEAL SSVTQLRLKD NCLSDAGVRK MTAPVRVMKR GLENLSLLDL
     SCNPEITDAG IGYLFSFRKL NCLDISGTGL KDIKAVKHKL QTHIGLVHSK VPLKEFDHSN
     CKTEGWADQI VLQWERVTLE AMKPQETLES RTAAQHFYGK RARTEAPGKY PLTEAHMNSS
     EKLQFYKEKA ADCHGPLLKH EALSSQESKK SKKRAFEEPE KEQGSSSQTS KQKYVCLAVE
     DWDLLNSY