ID   LRC42_XENLA             Reviewed;         417 AA.
AC   Q4KLV2; Q6DCF4;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-JAN-2009, sequence version 2.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Leucine-rich repeat-containing protein 42;
GN   Name=lrrc42;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LRRC42 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH78092.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAH98987.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC078092; AAH78092.1; ALT_INIT; mRNA.
DR   EMBL; BC098987; AAH98987.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q4KLV2; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR039631; LRRC42.
DR   PANTHER; PTHR31994; PTHR31994; 1.
DR   Pfam; PF13516; LRR_6; 3.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..417
FT                   /note="Leucine-rich repeat-containing protein 42"
FT                   /id="PRO_0000360042"
FT   REPEAT          167..188
FT                   /note="LRR 1"
FT   REPEAT          195..215
FT                   /note="LRR 2"
FT   REPEAT          227..248
FT                   /note="LRR 3"
FT   REPEAT          252..273
FT                   /note="LRR 4"
FT   REGION          360..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        360..386
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        245
FT                   /note="C -> S (in Ref. 1; AAH78092)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        323
FT                   /note="S -> L (in Ref. 1; AAH78092)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        370
FT                   /note="D -> V (in Ref. 1; AAH78092)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   417 AA;  47113 MW;  2B6A6831030CA0C2 CRC64;
     MFQCLEPERN EEAGLVYVRE KGKLSVIGSH SSELRTRPCR LFSKGFSVEL CGKQEDTSKH
     RQKPFIFTYT KEGSLRYSAK SLFTLTLELI SDNIQYVDSL MGFPDQIAEK LFTAAEAKQK
     FYAPCSGLMA LRKFTEAYGD LVLSSLCLRG RYLLVSERLE EIKSFQCLHS LDLSCCKLGD
     EHELLAHLSS DPMSSLTELY LKDNCLSNIG IQKMTASVRV LGRGLDKLKV LDLSSNPGIT
     DRGVCFLFGF KLLKFLDLSD TSIQDPSGTL KKIETKIGLV LSKKSIFQFD HTNCRTQGWA
     EQLLEQWESY ILSAIKPKDT LKSRNAAQQF YGKEKKQIPS DSGTFTLPAP VVQKQTHLQF
     FRPKEQKDPD SSNSEKRRHS TKRTGADCVQ EDCSIAPSTK RPRVTLTSSD WDLLNSY