ID   LRC43_MACFA             Reviewed;         654 AA.
AC   Q95JT3;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Leucine-rich repeat-containing protein 43;
GN   Name=LRRC43; ORFNames=QtsA-13548;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA   Terao K., Sugano S., Hashimoto K.;
RT   "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT   the human genome sequence.";
RL   BMC Genomics 3:36-36(2002).
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DR   EMBL; AB070096; BAB63041.1; -; mRNA.
DR   RefSeq; NP_001306447.1; NM_001319518.1.
DR   AlphaFoldDB; Q95JT3; -.
DR   SMR; Q95JT3; -.
DR   STRING; 9541.XP_005572534.1; -.
DR   GeneID; 102136332; -.
DR   CTD; 254050; -.
DR   eggNOG; KOG0531; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13855; LRR_8; 1.
DR   PROSITE; PS51450; LRR; 5.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..654
FT                   /note="Leucine-rich repeat-containing protein 43"
FT                   /id="PRO_0000311909"
FT   REPEAT          148..168
FT                   /note="LRR 1"
FT   REPEAT          170..191
FT                   /note="LRR 2"
FT   REPEAT          194..213
FT                   /note="LRR 3"
FT   REPEAT          221..242
FT                   /note="LRR 4"
FT   DOMAIN          256..294
FT                   /note="LRRCT"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          510..548
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        512..548
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   654 AA;  72610 MW;  9331BBA9D453806A CRC64;
     MEASYKSESE SEAWPGTQRP GTGTVSTAVR EHLRKLCLRE FPCGAGSWNK SRFLPQTWRT
     WRELVPKEED VVSPGEETVE ALLGLVRSPH SPWALLNDSN AEDSFLRELA IRNPLMITDT
     FFYSYFRSLR VVDKEVTLVD KDLLKFLKLE ELVLSANRIK EVDATNLPPT LKVLELYGNE
     ISSMECLCAH PPAGLQHLGL GHNKLLGPLE SLYVTADHWP NLVSLDLGFN DLTDLQSMVA
     SLRTLRHLRL LVLQGNPLAL VPYYRGLTID SLAQLCVLDD ITVSPNEKHL FRGLSLNGDL
     LAQEAQFVVT IGNIRGVLDT SVLDPEPGPE GPFVAYSYYV TYDFVRDEEG EAVEDTGELA
     EIVKPSPSSE LLVDESPEEV GEDVIKDIVG GVTEEVEGSL ESEVEESGES ELSVISGPST
     VLQTPRASAE ELAKLRLRID PRLCPSPGTV LFNTTHKPWA EVIPCGYEMQ HSLRDLVPLK
     AFLLAGTTVT IVEEKILSWP VVLPAVDSPL SAKRGKGEKD KKGKEKDRKG QGEKEPAKEW
     KVPKKKKELP KELRQDPPIL QVLGRGLVIL EPLLAGEPLV STVCNFGMVR TLTSDRLTLA
     RDSKKIKKVA KKEKPKAVNP IYESDYHPEP LTVEVQIQLN QCRSAEEALR MFAV