ID   LRC46_MACFA             Reviewed;         321 AA.
AC   Q4R747;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Leucine-rich repeat-containing protein 46;
GN   Name=LRRC46; ORFNames=QtsA-16355;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AB168981; BAE01077.1; -; mRNA.
DR   RefSeq; NP_001271513.1; NM_001284584.1.
DR   AlphaFoldDB; Q4R747; -.
DR   SMR; Q4R747; -.
DR   STRING; 9541.XP_005583574.1; -.
DR   Ensembl; ENSMFAT00000068134; ENSMFAP00000017592; ENSMFAG00000031915.
DR   GeneID; 101865879; -.
DR   CTD; 90506; -.
DR   VEuPathDB; HostDB:ENSMFAG00000031915; -.
DR   eggNOG; KOG0531; Eukaryota.
DR   GeneTree; ENSGT00940000161315; -.
DR   OMA; VSERWAS; -.
DR   OrthoDB; 1445923at2759; -.
DR   Proteomes; UP000233100; Chromosome 16.
DR   Bgee; ENSMFAG00000031915; Expressed in liver and 10 other tissues.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   SMART; SM00369; LRR_TYP; 2.
DR   PROSITE; PS51450; LRR; 5.
PE   2: Evidence at transcript level;
KW   Coiled coil; Leucine-rich repeat; Phosphoprotein; Reference proteome;
KW   Repeat.
FT   CHAIN           1..321
FT                   /note="Leucine-rich repeat-containing protein 46"
FT                   /id="PRO_0000223920"
FT   REPEAT          45..66
FT                   /note="LRR 1"
FT   REPEAT          67..88
FT                   /note="LRR 2"
FT   REPEAT          89..110
FT                   /note="LRR 3"
FT   REPEAT          111..132
FT                   /note="LRR 4"
FT   DOMAIN          142..184
FT                   /note="LRRCT"
FT   REGION          235..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          198..222
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        246..276
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         175
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9DAP0"
FT   MOD_RES         182
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9DAP0"
SQ   SEQUENCE   321 AA;  35598 MW;  6000F2205CBE63AF CRC64;
     MSGAKSAQGP EEGGVCITEA LITKRNLTFP EDEELSEKMF HTLDELQTVR LDREGITTIR
     NLEGLKNLHS LYLQGNKIQQ IENLACVPSL RFLSLAGNQI RQVENLLDLP CLQFLDLSEN
     LIETLKLDEF PQSLLILNLS GNSCTNQDSY RELVIEALPL LLDLDGQPVM ERWISDEEDE
     ASSEEEFPEL SGPFCSERGF LKELEQELSR HREHRQQAAL TQHLLRMEMQ PTLTNLPLLP
     GVPMAGDSSP STTPGQGEET VPEAVSSPQA SSPTKKPCSL IPRGRQNSLW GRKGVRASTV
     PKASVAEAPS TTKTMAKRSK K