ID   LRC57_RAT               Reviewed;         239 AA.
AC   Q5FVI3;
DT   21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Leucine-rich repeat-containing protein 57;
GN   Name=Lrrc57;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q8N9N7}; Lipid-
CC       anchor {ECO:0000250|UniProtKB:Q8N9N7}.
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DR   EMBL; BC089966; AAH89966.1; -; mRNA.
DR   RefSeq; NP_001012354.1; NM_001012354.2.
DR   RefSeq; XP_006234840.1; XM_006234778.2.
DR   RefSeq; XP_006234841.1; XM_006234779.3.
DR   AlphaFoldDB; Q5FVI3; -.
DR   SMR; Q5FVI3; -.
DR   BioGRID; 259901; 1.
DR   STRING; 10116.ENSRNOP00000050922; -.
DR   iPTMnet; Q5FVI3; -.
DR   PhosphoSitePlus; Q5FVI3; -.
DR   jPOST; Q5FVI3; -.
DR   PaxDb; Q5FVI3; -.
DR   PRIDE; Q5FVI3; -.
DR   Ensembl; ENSRNOT00000049756; ENSRNOP00000050922; ENSRNOG00000009143.
DR   GeneID; 311346; -.
DR   KEGG; rno:311346; -.
DR   UCSC; RGD:1307128; rat.
DR   CTD; 255252; -.
DR   RGD; 1307128; Lrrc57.
DR   eggNOG; KOG0619; Eukaryota.
DR   GeneTree; ENSGT00940000157393; -.
DR   HOGENOM; CLU_000288_18_15_1; -.
DR   InParanoid; Q5FVI3; -.
DR   OMA; DKYMERY; -.
DR   OrthoDB; 1348484at2759; -.
DR   PhylomeDB; Q5FVI3; -.
DR   PRO; PR:Q5FVI3; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000009143; Expressed in testis and 20 other tissues.
DR   Genevisible; Q5FVI3; RN.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00369; LRR_TYP; 6.
DR   PROSITE; PS51450; LRR; 7.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Lipoprotein; Membrane; Myristate; Reference proteome;
KW   Repeat.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N9N7"
FT   CHAIN           2..239
FT                   /note="Leucine-rich repeat-containing protein 57"
FT                   /id="PRO_0000227780"
FT   REPEAT          39..60
FT                   /note="LRR 1"
FT   REPEAT          63..85
FT                   /note="LRR 2"
FT   REPEAT          86..107
FT                   /note="LRR 3"
FT   REPEAT          109..131
FT                   /note="LRR 4"
FT   REPEAT          132..153
FT                   /note="LRR 5"
FT   REPEAT          154..175
FT                   /note="LRR 6"
FT   REPEAT          177..197
FT                   /note="LRR 7"
FT   REPEAT          202..222
FT                   /note="LRR 8"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N9N7"
SQ   SEQUENCE   239 AA;  26724 MW;  A89E6DC32B5DA3DA CRC64;
     MGNSALRAHV ETAQKTGVFQ LKDRGLTEFP SELQKLTSNL RTIDLSNNKI DSLPPLIIGK
     FTLLKSLSLN NNKLTVLPDE LCNLKKLETL SLNNNHLREL PSSFGQLSAL KTLSLSGNQL
     GALPPQLCSL RHLDVVDLSK NQIRSIPDTV GELQAIELNL NQNQISQISV RISCCPRLKV
     LRLEENCLEL SMLPQSILSD SQICLLAVEG NLFEIKKLRE LEGYDKYMER FTATKKKFA