ID   LRC63_RAT               Reviewed;         607 AA.
AC   Q4V8G0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Leucine-rich repeat-containing protein 63;
GN   Name=Lrrc63;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC097406; AAH97406.1; -; mRNA.
DR   RefSeq; NP_001019974.1; NM_001024803.1.
DR   RefSeq; XP_006252387.1; XM_006252325.3.
DR   RefSeq; XP_006252388.1; XM_006252326.3.
DR   RefSeq; XP_006252389.1; XM_006252327.3.
DR   AlphaFoldDB; Q4V8G0; -.
DR   SMR; Q4V8G0; -.
DR   STRING; 10116.ENSRNOP00000055096; -.
DR   PaxDb; Q4V8G0; -.
DR   PRIDE; Q4V8G0; -.
DR   Ensembl; ENSRNOT00000058294; ENSRNOP00000055096; ENSRNOG00000038291.
DR   GeneID; 364427; -.
DR   KEGG; rno:364427; -.
DR   UCSC; RGD:1559507; rat.
DR   CTD; 220416; -.
DR   RGD; 1559507; Lrrc63.
DR   eggNOG; KOG0619; Eukaryota.
DR   GeneTree; ENSGT00710000106860; -.
DR   HOGENOM; CLU_027651_0_0_1; -.
DR   InParanoid; Q4V8G0; -.
DR   OrthoDB; 1295759at2759; -.
DR   PhylomeDB; Q4V8G0; -.
DR   TreeFam; TF329649; -.
DR   PRO; PR:Q4V8G0; -.
DR   Proteomes; UP000002494; Chromosome 15.
DR   Bgee; ENSRNOG00000038291; Expressed in testis and 2 other tissues.
DR   ExpressionAtlas; Q4V8G0; baseline.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00369; LRR_TYP; 4.
DR   PROSITE; PS51450; LRR; 4.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..607
FT                   /note="Leucine-rich repeat-containing protein 63"
FT                   /id="PRO_0000320630"
FT   REPEAT          357..378
FT                   /note="LRR 1"
FT   REPEAT          380..401
FT                   /note="LRR 2"
FT   REPEAT          403..424
FT                   /note="LRR 3"
FT   REPEAT          426..447
FT                   /note="LRR 4"
FT   REPEAT          449..470
FT                   /note="LRR 5"
FT   REPEAT          471..497
FT                   /note="LRR 6"
FT   REPEAT          498..524
FT                   /note="LRR 7"
SQ   SEQUENCE   607 AA;  69217 MW;  F45142DA24AB821B CRC64;
     MRKRIYHSFK TQQHPLLLRR PLPPKLPKLP LVKKKVRIVQ TGSAREPQEA RRKFDTEESA
     LVKIDQSVSQ PQKPASVQNV CLDYEHDEPE RVVNIFPHPH GVRRLHWKVP KSAAGSMFIP
     RCLSASSRVF RKTLSQIKRA RKSLKSKQDE DLTKKPFSNT LVISEELSKP LPPSYSRLIA
     SRFKHSGTKF RPAPKISHYI QELPLLKDVK ETVLSPISSA SSAIPEPEWS ERPLPKTTIG
     KVIQLNTGSL PPAHSLPTPA LPRKPPRQIM IENAVMTRKT ETQKPVEITL RPTRRLDPDA
     HVLRGDGFKA VGATRSETIL ALTTLAIINC QIYGRNALNF KGFFLAQCPD LTSVAFQLVY
     LNLSYNDLHQ FPGEVLYLQN LQVLKLRNNP IREIPSEIQQ LKYLRKFTIA FNFITSLPAG
     LFCLNYLEEL DVSYNEIENI PNEIQKLRSL EKLTVDGTNI TAFPPGILKL NLVKLEFENT
     FTIPPFWLEN SCNNPPRLTH ICSLFIVKNN LHKILDYDPV VVQKYLISTS DCDWCHGPKF
     GEGFGIIRSC NIFGLSHVPI KFHVCSLSCY LEIRESSFVL EGFPSRRIAL NMDWVKERKV
     SNVSFYL