ID   LRIQ3_RAT               Reviewed;         633 AA.
AC   Q6AYL8;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Leucine-rich repeat and IQ domain-containing protein 3;
DE   AltName: Full=Leucine-rich repeat-containing protein 44;
GN   Name=Lrriq3; Synonyms=Lrrc44;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC078994; AAH78994.1; -; mRNA.
DR   RefSeq; NP_001019478.1; NM_001024307.1.
DR   AlphaFoldDB; Q6AYL8; -.
DR   SMR; Q6AYL8; -.
DR   STRING; 10116.ENSRNOP00000012841; -.
DR   PaxDb; Q6AYL8; -.
DR   PRIDE; Q6AYL8; -.
DR   Ensembl; ENSRNOT00000012841; ENSRNOP00000012841; ENSRNOG00000009555.
DR   GeneID; 499732; -.
DR   KEGG; rno:499732; -.
DR   CTD; 127255; -.
DR   RGD; 1591943; Lrriq3.
DR   eggNOG; KOG0531; Eukaryota.
DR   GeneTree; ENSGT00390000004404; -.
DR   HOGENOM; CLU_029934_0_0_1; -.
DR   InParanoid; Q6AYL8; -.
DR   OMA; FATHPKQ; -.
DR   OrthoDB; 795526at2759; -.
DR   PhylomeDB; Q6AYL8; -.
DR   TreeFam; TF329557; -.
DR   PRO; PR:Q6AYL8; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   Bgee; ENSRNOG00000009555; Expressed in testis and 11 other tissues.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF12799; LRR_4; 1.
DR   SMART; SM00369; LRR_TYP; 2.
DR   PROSITE; PS50096; IQ; 1.
DR   PROSITE; PS51450; LRR; 3.
PE   2: Evidence at transcript level;
KW   Coiled coil; Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..633
FT                   /note="Leucine-rich repeat and IQ domain-containing protein
FT                   3"
FT                   /id="PRO_0000311196"
FT   REPEAT          51..72
FT                   /note="LRR 1"
FT   REPEAT          73..94
FT                   /note="LRR 2"
FT   REPEAT          98..119
FT                   /note="LRR 3"
FT   DOMAIN          132..179
FT                   /note="LRRCT"
FT   DOMAIN          215..244
FT                   /note="IQ"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT   REGION          322..343
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          556..616
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   633 AA;  75120 MW;  1BD0A2B30B8C8355 CRC64;
     MFHGTITKEL TSHEEWSHYN ENIVEDQKDF VFVKYNGLHL KSMENLQSCI SLRVCIFSNN
     FVTDIQPLQG CKKLIKLDLH GNQIKTLPDR TFWNGLKNLK LLYLHDNGFA KLKNICVLSG
     CVNLVGLTMF DCPVSLKKGY RHVLVNSIWP LKALDHHVIS DEEIIQNWHL PERFKTFSQS
     LFFNICPAPI KGTTYEDEIK NIKHIISRIN EILAHNSPVL IIQRWIRGFI VRKHLSPYFT
     RKRHHDRMIR VLETKLICIG RNNEDKFLED IFLIKPESNI KGKVAHWKQM RYSPDDFKYS
     TEYRKHISCL SYELKTKDIA GNSKQPRHHI QKGQNEMKSD SEDEEVDTKF RISAMKIPLC
     PSRSLKYRAM LKEIKWDYFP EYLQPLPATR QKPQVKRETH EELKERRNFL ASQRAGMDLH
     LFNDIDKYYS EQRQQEEEAR KFAATAAAQV AQERARLNTS ENLRKKISMA RKLMQKDNET
     IQKGLRHIWK ERLNYLEKVR ERKSMFLAEK KLNAADQSLV LSLNNERSIL LRGIIQVDKL
     KRDLSEMKAK HFDVIEKREK RKYKQNLLTE MKKLRAEEIH KRHCEERFVI DTLIFQKGCE
     RLEEAKAKVE FINTYYTSKS HKKYHNKTML NHI