ID   LRPB_BACSU              Reviewed;         149 AA.
AC   P96653;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=HTH-type transcriptional regulator LrpB;
GN   Name=lrpB; Synonyms=yddP; OrderedLocusNames=BSU05060;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=11902725; DOI=10.1046/j.1365-2958.1997.4491805.x;
RA   Dartois V., Liu J., Hoch J.A.;
RT   "Alterations in the flow of one-carbon units affect KinB-dependent
RT   sporulation in Bacillus subtilis.";
RL   Mol. Microbiol. 25:39-51(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Kasahara Y., Nakai S., Lee S., Sadaie Y., Ogasawara N.;
RT   "A 148 kbp sequence of the region between 35 and 47 degree of the Bacillus
RT   subtilis genome.";
RL   Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Negative regulation of glyA transcription and kinB-dependent
CC       sporulation. {ECO:0000269|PubMed:11902725}.
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DR   EMBL; L44122; AAR24606.1; -; Genomic_DNA.
DR   EMBL; AB001488; BAA19342.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12313.1; -; Genomic_DNA.
DR   PIR; E69653; E69653.
DR   RefSeq; NP_388387.1; NC_000964.3.
DR   RefSeq; WP_003246612.1; NZ_JNCM01000031.1.
DR   AlphaFoldDB; P96653; -.
DR   SMR; P96653; -.
DR   STRING; 224308.BSU05060; -.
DR   PaxDb; P96653; -.
DR   PRIDE; P96653; -.
DR   EnsemblBacteria; CAB12313; CAB12313; BSU_05060.
DR   GeneID; 939912; -.
DR   KEGG; bsu:BSU05060; -.
DR   PATRIC; fig|224308.179.peg.537; -.
DR   eggNOG; COG1522; Bacteria.
DR   InParanoid; P96653; -.
DR   OMA; CYGPRCV; -.
DR   PhylomeDB; P96653; -.
DR   BioCyc; BSUB:BSU05060-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR   InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01037; AsnC_trans_reg; 1.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..149
FT                   /note="HTH-type transcriptional regulator LrpB"
FT                   /id="PRO_0000111739"
FT   DOMAIN          3..64
FT                   /note="HTH asnC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT   DNA_BIND        22..41
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
SQ   SEQUENCE   149 AA;  17326 MW;  3FE7BCC2F4C039B8 CRC64;
     MQIDSIDFQI LQLLNKNARI QWKEIGEKIH MTGQAVGNRI KKMEDNGIIK AYSIVVDELK
     MGFSFTAFVF FFMNAYMHDD LLKFIATRNE ISEAHRVSGD ACYLLKVTVH SQEVLNHLLN
     DLLKYGNYQL YLSIKEVKKH YNTSLMSDE