LRR1_ARATH
ID LRR1_ARATH Reviewed; 218 AA.
AC Q9FPJ5;
DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 163.
DE RecName: Full=Leucine-rich repeat protein 1 {ECO:0000303|PubMed:19712067};
DE Short=AtLRR1 {ECO:0000303|PubMed:19712067};
DE Flags: Precursor;
GN Name=LRR1 {ECO:0000303|PubMed:19712067};
GN OrderedLocusNames=At5g21090 {ECO:0000312|Araport:AT5G21090};
GN ORFNames=T10F18.120 {ECO:0000312|EMBL:AAG40341.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAG40341.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP INDUCTION BY METHYL JASMONATE.
RX PubMed=16623907; DOI=10.1111/j.1365-313x.2006.02712.x;
RA Li J., Brader G., Kariola T., Palva E.T.;
RT "WRKY70 modulates the selection of signaling pathways in plant defense.";
RL Plant J. 46:477-491(2006).
RN [6]
RP IDENTIFICATION, FUNCTION, AND INTERACTION WITH HIR1.
RX PubMed=19712067; DOI=10.1111/j.1365-3040.2009.02039.x;
RA Zhou L., Cheung M.Y., Zhang Q., Lei C.L., Zhang S.H., Sun S.S., Lam H.M.;
RT "A novel simple extracellular leucine-rich repeat (eLRR) domain protein
RT from rice (OsLRR1) enters the endosomal pathway and interacts with the
RT hypersensitive-induced reaction protein 1 (OsHIR1).";
RL Plant Cell Environ. 32:1804-1820(2009).
CC -!- FUNCTION: Involved in plant defense response.
CC {ECO:0000269|PubMed:19712067}.
CC -!- SUBUNIT: Interacts with HIR1. {ECO:0000269|PubMed:19712067}.
CC -!- INDUCTION: Up-regulated by methyl jasmonate.
CC {ECO:0000269|PubMed:16623907}.
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DR EMBL; AC140977; AAO73897.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92930.1; -; Genomic_DNA.
DR EMBL; AF324989; AAG40341.1; -; mRNA.
DR EMBL; AF370543; AAK48970.1; -; mRNA.
DR EMBL; AY081542; AAM10104.1; -; mRNA.
DR EMBL; BT002517; AAO00877.1; -; mRNA.
DR EMBL; BT006268; AAP13376.1; -; mRNA.
DR EMBL; AK317417; BAH20085.1; -; mRNA.
DR RefSeq; NP_197608.1; NM_122117.4.
DR AlphaFoldDB; Q9FPJ5; -.
DR SMR; Q9FPJ5; -.
DR STRING; 3702.AT5G21090.1; -.
DR PaxDb; Q9FPJ5; -.
DR PRIDE; Q9FPJ5; -.
DR ProteomicsDB; 238674; -.
DR EnsemblPlants; AT5G21090.1; AT5G21090.1; AT5G21090.
DR GeneID; 832233; -.
DR Gramene; AT5G21090.1; AT5G21090.1; AT5G21090.
DR KEGG; ath:AT5G21090; -.
DR Araport; AT5G21090; -.
DR TAIR; locus:2178968; AT5G21090.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_000288_18_9_1; -.
DR InParanoid; Q9FPJ5; -.
DR OMA; XFLLLAI; -.
DR OrthoDB; 1269119at2759; -.
DR PhylomeDB; Q9FPJ5; -.
DR PRO; PR:Q9FPJ5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FPJ5; baseline and differential.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IC:TAIR.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
PE 1: Evidence at protein level;
KW Leucine-rich repeat; Plant defense; Reference proteome; Repeat; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..218
FT /note="Leucine-rich repeat protein 1"
FT /evidence="ECO:0000255"
FT /id="PRO_5009348379"
FT REPEAT 94..117
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 119..140
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 141..165
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 167..190
FT /note="LRR 4"
FT /evidence="ECO:0000255"
SQ SEQUENCE 218 AA; 24097 MW; 39B5CB5F85723A39 CRC64;
MASRNYRWEL FAASLTLTLA LIHLVEANSE GDALYALRRS LTDPDHVLQS WDPTLVNPCT
WFHVTCNQDN RVTRVDLGNS NLSGHLAPEL GKLEHLQYLE LYKNNIQGTI PSELGNLKNL
ISLDLYNNNL TGIVPTSLGK LKSLVFLRLN DNRLTGPIPR ALTAIPSLKV VDVSSNDLCG
TIPTNGPFAH IPLQNFENNP RLEGPELLGL ASYDTNCT
