LRR1_CAPAN
ID LRR1_CAPAN Reviewed; 197 AA.
AC Q8H6W9;
DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 2.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Leucine-rich repeat protein 1 {ECO:0000303|PubMed:14984927};
DE AltName: Full=Capsicum annuum-induced protein 23 {ECO:0000303|PubMed:10656596};
DE Flags: Precursor;
GN Name=LRR1 {ECO:0000303|PubMed:14984927};
GN Synonyms=CAI23 {ECO:0000303|PubMed:10656596};
OS Capsicum annuum (Capsicum pepper).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Capsiceae; Capsicum.
OX NCBI_TaxID=4072 {ECO:0000312|EMBL:AAN62015.2};
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION BY PATHOGEN.
RC TISSUE=Leaf;
RX PubMed=10656596; DOI=10.1094/mpmi.2000.13.1.136;
RA Jung H.W., Hwang B.K.;
RT "Isolation, partial sequencing, and expression of pathogenesis-related cDNA
RT genes from pepper leaves infected by Xanthomonas campestris pv.
RT vesicatoria.";
RL Mol. Plant Microbe Interact. 13:136-142(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INDUCTION BY PATHOGEN AND ABIOTIC
RP STRESS, AND TISSUE SPECIFICITY.
RC TISSUE=Leaf;
RX PubMed=14984927; DOI=10.1016/s0167-4781(03)00120-9;
RA Jung E.H., Jung H.W., Lee S.C., Han S.W., Heu S., Hwang B.K.;
RT "Identification of a novel pathogen-induced gene encoding a leucine-rich
RT repeat protein expressed in phloem cells of Capsicum annuum.";
RL Biochim. Biophys. Acta 1676:211-222(2004).
RN [3]
RP FUNCTION, INTERACTION WITH HIR1, AND INDUCTION BY PATHOGEN AND HORMONES.
RX PubMed=20507517; DOI=10.1111/j.1364-3703.2007.00410.x;
RA Jung H.W., Hwang B.K.;
RT "The leucine-rich repeat (LRR) protein, CaLRR1, interacts with the
RT hypersensitive induced reaction (HIR) protein, CaHIR1, and suppresses cell
RT death induced by the CaHIR1 protein.";
RL Mol. Plant Pathol. 8:503-514(2007).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, AND INTERACTION WITH PR10.
RX PubMed=22492811; DOI=10.1105/tpc.112.095869;
RA Choi D.S., Hwang I.S., Hwang B.K.;
RT "Requirement of the cytosolic interaction between PATHOGENESIS-RELATED
RT PROTEIN10 and LEUCINE-RICH REPEAT PROTEIN1 for cell death and defense
RT signaling in pepper.";
RL Plant Cell 24:1675-1690(2012).
CC -!- FUNCTION: Involved in biotic and abiotic stress response, but not in
CC systemic acquired resistance (SAR) (PubMed:14984927). Acts as a
CC negative regulator of HIR1-mediated cell death responses
CC (PubMed:20507517). Acts as a positive regulator of cell death induction
CC by PR10 by promoting its phosphorylation and its ribonuclease activity
CC (PubMed:22492811). {ECO:0000269|PubMed:14984927,
CC ECO:0000269|PubMed:20507517, ECO:0000269|PubMed:22492811}.
CC -!- SUBUNIT: Interacts (via LRR domain) with HIR1 (PubMed:20507517).
CC Interacts with PR10 (PubMed:22492811). {ECO:0000269|PubMed:20507517,
CC ECO:0000269|PubMed:22492811}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22492811}.
CC -!- TISSUE SPECIFICITY: Expressed in phloem tissues of leaves, stems and
CC green fruits during pathogen infection. {ECO:0000269|PubMed:14984927}.
CC -!- INDUCTION: Strongly up-regulated by pathogen infection
CC (PubMed:10656596, PubMed:14984927, PubMed:20507517). Up-regulated by
CC high salt and wounding (PubMed:14984927). Not induced by ethephon,
CC ethylene, abscisic acid, salicylic acid or methyl jasmonate
CC (PubMed:10656596, PubMed:20507517). {ECO:0000269|PubMed:10656596,
CC ECO:0000269|PubMed:14984927, ECO:0000269|PubMed:20507517}.
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DR EMBL; AY237117; AAN62015.2; -; mRNA.
DR AlphaFoldDB; Q8H6W9; -.
DR SMR; Q8H6W9; -.
DR Proteomes; UP000189700; Genome assembly.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Leucine-rich repeat; Repeat; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..197
FT /note="Leucine-rich repeat protein 1"
FT /evidence="ECO:0000255"
FT /id="PRO_5004306550"
FT REPEAT 86..110
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 111..134
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 136..158
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 161..188
FT /note="LRR 4"
FT /evidence="ECO:0000255"
SQ SEQUENCE 197 AA; 21400 MW; 93AF73C5D76D8EB5 CRC64;
MRFIALVFLV GALAIIAVEC NSEGDALNAF KMNMLDPNNA LQSWDPTLVN PCTWLHVTCN
IQNSVTRVDL GGANLSGILT PQLGVLYNLQ YLQVENNSIS GAIPRELRNL TNLLSLGLEN
NKLSGTIPSS LGNLKSLRWM RLNSNRLSGE IPISVLKLVL WGNLQLMNVS DNKLAGTVPL
ANKTGFAITT IVQDMKA
