LRR2_ARATH
ID LRR2_ARATH Reviewed; 218 AA.
AC Q6NQP4; F4J0G6; Q67XM7; Q9LZH3;
DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 146.
DE RecName: Full=Leucine-rich repeat protein 2 {ECO:0000305};
DE Short=AtLRR2 {ECO:0000305};
DE Flags: Precursor;
GN Name=LRR2 {ECO:0000305};
GN OrderedLocusNames=At3g43740 {ECO:0000312|Araport:AT3G43740};
GN ORFNames=T28A8.30 {ECO:0000312|EMBL:CAB83146.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAQ62408.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably involved in plant defense response.
CC {ECO:0000250|UniProtKB:Q9FPJ5}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q6NQP4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6NQP4-2; Sequence=VSP_058843;
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB83146.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL162691; CAB83146.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77824.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE77825.1; -; Genomic_DNA.
DR EMBL; BT010407; AAQ62408.1; -; mRNA.
DR EMBL; AK175133; BAD42896.1; -; mRNA.
DR EMBL; AK175524; BAD43287.1; -; mRNA.
DR EMBL; AK176628; BAD44391.1; -; mRNA.
DR EMBL; AK176756; BAD44519.1; -; mRNA.
DR EMBL; AK176791; BAD44554.1; -; mRNA.
DR PIR; T47410; T47410.
DR RefSeq; NP_189960.2; NM_114242.4. [Q6NQP4-1]
DR RefSeq; NP_974381.1; NM_202652.3. [Q6NQP4-2]
DR AlphaFoldDB; Q6NQP4; -.
DR SMR; Q6NQP4; -.
DR PRIDE; Q6NQP4; -.
DR ProteomicsDB; 238800; -. [Q6NQP4-1]
DR EnsemblPlants; AT3G43740.1; AT3G43740.1; AT3G43740. [Q6NQP4-1]
DR EnsemblPlants; AT3G43740.2; AT3G43740.2; AT3G43740. [Q6NQP4-2]
DR GeneID; 823485; -.
DR Gramene; AT3G43740.1; AT3G43740.1; AT3G43740. [Q6NQP4-1]
DR Gramene; AT3G43740.2; AT3G43740.2; AT3G43740. [Q6NQP4-2]
DR KEGG; ath:AT3G43740; -.
DR Araport; AT3G43740; -.
DR TAIR; locus:2101064; AT3G43740.
DR HOGENOM; CLU_000288_18_9_1; -.
DR OMA; NFEHNPR; -.
DR OrthoDB; 1260451at2759; -.
DR PhylomeDB; Q6NQP4; -.
DR PRO; PR:Q6NQP4; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q6NQP4; baseline and differential.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Leucine-rich repeat; Plant defense;
KW Reference proteome; Repeat; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..218
FT /note="Leucine-rich repeat protein 2"
FT /evidence="ECO:0000255"
FT /id="PRO_5009345181"
FT REPEAT 69..93
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 94..117
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 119..141
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 142..165
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT REPEAT 167..190
FT /note="LRR 5"
FT /evidence="ECO:0000255"
FT VAR_SEQ 99
FT /note="L -> LYGIITLLPFDYLKTFTLSVTHITFCFESYS (in isoform 2)"
FT /id="VSP_058843"
FT CONFLICT 51
FT /note="W -> R (in Ref. 4; BAD44554)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 218 AA; 24125 MW; A74B358758EBF52F CRC64;
MVAQNSRREL LAASLILTLA LIRLTEANSE GDALHALRRS LSDPDNVVQS WDPTLVNPCT
WFHVTCNQHH QVTRLDLGNS NLSGHLVPEL GKLEHLQYLE LYKNEIQGTI PSELGNLKSL
ISLDLYNNNL TGKIPSSLGK LKSLVFLRLN ENRLTGPIPR ELTVISSLKV VDVSGNDLCG
TIPVEGPFEH IPMQNFENNL RLEGPELLGL ASYDTNCT
