LRRX1_DICDI
ID LRRX1_DICDI Reviewed; 1492 AA.
AC Q54G05;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Putative leucine-rich repeat-containing protein DDB_G0290503;
GN ORFNames=DDB_G0290503;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000164; EAL62112.1; -; Genomic_DNA.
DR RefSeq; XP_635612.1; XM_630520.1.
DR AlphaFoldDB; Q54G05; -.
DR SMR; Q54G05; -.
DR PaxDb; Q54G05; -.
DR EnsemblProtists; EAL62112; EAL62112; DDB_G0290503.
DR GeneID; 8627684; -.
DR KEGG; ddi:DDB_G0290503; -.
DR dictyBase; DDB_G0290503; -.
DR eggNOG; ENOG502RDH9; Eukaryota.
DR HOGENOM; CLU_249111_0_0_1; -.
DR InParanoid; Q54G05; -.
DR OMA; MAAMFKN; -.
DR PhylomeDB; Q54G05; -.
DR PRO; PR:Q54G05; -.
DR Proteomes; UP000002195; Chromosome 5.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..1492
FT /note="Putative leucine-rich repeat-containing protein
FT DDB_G0290503"
FT /id="PRO_0000330593"
FT DOMAIN 2..111
FT /note="PH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT REPEAT 123..144
FT /note="LRR 1"
FT REPEAT 180..204
FT /note="LRR 2"
FT REPEAT 258..284
FT /note="LRR 3"
FT REPEAT 329..351
FT /note="LRR 4"
FT REPEAT 352..375
FT /note="LRR 5"
FT REPEAT 389..413
FT /note="LRR 6"
FT REPEAT 439..462
FT /note="LRR 7"
FT REPEAT 519..543
FT /note="LRR 8"
FT REPEAT 551..575
FT /note="LRR 9"
FT REPEAT 579..603
FT /note="LRR 10"
FT REPEAT 632..656
FT /note="LRR 11"
FT REPEAT 728..752
FT /note="LRR 12"
FT REPEAT 806..830
FT /note="LRR 13"
FT REPEAT 831..855
FT /note="LRR 14"
FT REPEAT 895..919
FT /note="LRR 15"
FT REPEAT 927..951
FT /note="LRR 16"
FT REPEAT 955..979
FT /note="LRR 17"
FT REPEAT 1013..1036
FT /note="LRR 18"
FT REPEAT 1044..1068
FT /note="LRR 19"
FT REPEAT 1138..1164
FT /note="LRR 20"
FT REPEAT 1210..1232
FT /note="LRR 21"
FT REPEAT 1424..1444
FT /note="LRR 22"
FT REPEAT 1445..1468
FT /note="LRR 23"
FT REGION 1272..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1274..1292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1492 AA; 174723 MW; 27BF3E671FD7E122 CRC64;
MSILLEGYLE KQGEKGIYKS YKNRYFSLAK NGFDLHYFES PPPKDVSFSS STQSSTALSL
GYLDIRQVTS IKKVDGNFVF HVEVPGRVYI LRAKNDTEIN YWIEGIKDAI KYHEINSSQV
QVLDGLIKTK DNDIIKLREK IKHLNEKHQE SEKRYQEKEK KFEEQRTIEI QETTKKEQEI
KSLTLQLSSK DESMKSLEKQ VEKLVDIEHR SEIEQTKKDN EILKLTEKIK EIQLIENLNS
TNDSKVNQLL EDNIKRLQES LNEIKDENND LQSLIDTQKQ QFEKRINQYQ LEIQDKENEL
NEMNQQSLSQ VKSFQQSLQQ SQLDLENDKN QFSTKLQLVN NEIQSLKSIV DDKLKEIQLK
DNQLTQLNQQ HEIDNNKNNQ MILELNDNIS KISNQLNEKD NKIQELSKQS IDKQKEIENS
TSSSDQLQLK LNDISNELLE KLNDINQLSN KLQDKENQIL EINNKLNEKE NQLISKDNQL
NQLIENNESS SDELKLKLNQ LSDELQEKDE KLLNNQSVIN ELQSNLNENQ NKINELIENN
QSSSDELKLK LNQLSDKLQE KDEKLKSLES SIIERDEKID QLQDNLNEKQ DKINELVENN
ESSSDELQSK LIQLSDQLQE KDEKLLNNQS IINELQSNLN ENQNKINELI ENNQSSSDEL
NSKLIKLSDE LKDKNENVRS LETSIIENQD KLDQLIQSNQ VTVNELQSKL NEKEININQL
IENNQSSLDE LQSKLNEKQN EINQLIENNQ SSSDELQSKL NEKHQEISEL QSKLNELIEN
NESSSDELQS KLIQLSDELK EKDEKLKSLD SIIIENQEKL VQLTKSNQDS LDELQSKLNE
KQNEINELIE NNQSSSNELQ SKLNEKQNEI NLLIENNQSS SDELQSKLNE KHQEINELQS
KLNEKQNKIN ELVENNESSS DELQSKLIQL SDQLQEKENQ LKSFESSIIE RDEKLNQLQS
KLNEKQNEID QITENNQSSL DELQSNLNEK QNEINQLIEN NQSSLDELQS KLNEKLNEIN
EKDNKINELI QTNESLSKDQ QSKFENLEQE LEEKNNKILD LNSQIIDVNH QFSEKENELN
QLQLKLIEKD QEIENQNNKI IDINNQLNEK EKEININNDN DNNNEENIQL IEELKEKLQD
LENELNLEKD TVNEKNDDIN ELKEEIKLIS EKLSEKEQEL NEMINDYDES LNEINDQKDL
VKSLNERLTN AHLKINEKDN EIHSLSKEGF NEIQSQLNLI TNQLSEKDNL LIEKSQIISD
LELQLRESYK ERSSSSSLHQ QQQMISPDLS NSNDELIVEK EEIINELKEK NQQLEQQLQD
LCQQFNKNKQ ENELKCQQLE EENDGWKNEI DTLNQRLKTQ SLNTSPDSSE LQQQLDIISN
QELNIKQLEK ELQDKSGKID NLEYQVEEMN KQYHIDINQK TNESSEKLQS IQLEIDTIRE
KYFFAIARSL KLQGAQMGWS MSRSIFDMFD EIKSLNINFD EWPIWISNQL EK