LRX4_ARATH
ID LRX4_ARATH Reviewed; 494 AA.
AC Q9LHF1;
DT 13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=Leucine-rich repeat extensin-like protein 4;
DE Short=AtLRX4;
DE Short=LRR/EXTENSIN4;
DE AltName: Full=Cell wall hydroxyproline-rich glycoprotein;
DE Flags: Precursor;
GN Name=LRX4; OrderedLocusNames=At3g24480; ORFNames=MXP5.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12644681; DOI=10.1104/pp.102.014928;
RA Baumberger N., Doesseger B., Guyot R., Diet A., Parsons R.L., Clark M.A.,
RA Simmons M.P., Bedinger P., Goff S.A., Ringli C., Keller B.;
RT "Whole-genome comparison of leucine-rich repeat extensins in Arabidopsis
RT and rice. A conserved family of cell wall proteins form a vegetative and a
RT reproductive clade.";
RL Plant Physiol. 131:1313-1326(2003).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=17272265; DOI=10.1074/mcp.m600408-mcp200;
RA Maor R., Jones A., Nuehse T.S., Studholme D.J., Peck S.C., Shirasu K.;
RT "Multidimensional protein identification technology (MudPIT) analysis of
RT ubiquitinated proteins in plants.";
RL Mol. Cell. Proteomics 6:601-610(2007).
CC -!- FUNCTION: Modulates cell morphogenesis by regulating cell wall
CC formation and assembly, and/or growth polarization. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000250|UniProtKB:O48809}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves and flowers,
CC mostly in vascular tissues. {ECO:0000269|PubMed:12644681}.
CC -!- PTM: Hydroxylated on proline residues in the S-P-P-P-P repeat.
CC {ECO:0000250}.
CC -!- PTM: O-glycosylated on hydroxyprolines. {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP002048; BAB01951.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76902.1; -; Genomic_DNA.
DR RefSeq; NP_189091.1; NM_113355.2.
DR AlphaFoldDB; Q9LHF1; -.
DR SMR; Q9LHF1; -.
DR BioGRID; 7369; 1.
DR STRING; 3702.AT3G24480.1; -.
DR PaxDb; Q9LHF1; -.
DR PRIDE; Q9LHF1; -.
DR ProteomicsDB; 238503; -.
DR EnsemblPlants; AT3G24480.1; AT3G24480.1; AT3G24480.
DR GeneID; 822038; -.
DR Gramene; AT3G24480.1; AT3G24480.1; AT3G24480.
DR KEGG; ath:AT3G24480; -.
DR Araport; AT3G24480; -.
DR TAIR; locus:2094854; AT3G24480.
DR eggNOG; ENOG502QQ2D; Eukaryota.
DR HOGENOM; CLU_000288_23_5_1; -.
DR InParanoid; Q9LHF1; -.
DR OMA; VNWIGSN; -.
DR OrthoDB; 670436at2759; -.
DR PhylomeDB; Q9LHF1; -.
DR PRO; PR:Q9LHF1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LHF1; baseline and differential.
DR Genevisible; Q9LHF1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0009505; C:plant-type cell wall; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0005199; F:structural constituent of cell wall; ISS:TAIR.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
PE 1: Evidence at protein level;
KW Cell wall; Cell wall biogenesis/degradation; Glycoprotein; Hydroxylation;
KW Leucine-rich repeat; Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..494
FT /note="Leucine-rich repeat extensin-like protein 4"
FT /id="PRO_0000395464"
FT REPEAT 121..145
FT /note="LRR 1"
FT REPEAT 146..168
FT /note="LRR 2"
FT REPEAT 169..193
FT /note="LRR 3"
FT REPEAT 194..217
FT /note="LRR 4"
FT REPEAT 219..240
FT /note="LRR 5"
FT REPEAT 242..263
FT /note="LRR 6"
FT REPEAT 264..287
FT /note="LRR 7"
FT REPEAT 289..311
FT /note="LRR 8"
FT REPEAT 312..335
FT /note="LRR 9"
FT REGION 404..494
FT /note="Contains the Ser-Pro(4) repeats"
FT REGION 422..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 60
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 94
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 106
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 289
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 340
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 494 AA; 54703 MW; A239C3AC0F21A2E3 CRC64;
MKNNTTQSLL LLLLFFFFFF EISHSLSISS NAPLSDTEVR FIQRRQLLYY RDEFGDRGEN
VTVDPSLIFE NPRLRSAYIA LQAWKQAILS DPNNITVNWI GSNVCNYTGV FCSKALDNRK
IRTVAGIDLN HADIAGYLPE ELGLLTDLAL FHVNSNRFCG TVPHKFKQLK LLFELDLSNN
RFAGKFPTVV LHLPSLKFLD LRFNEFEGTV PKELFSKNLD AIFINHNRFR FELPENFGDS
PVSVIVLANN HFHGCIPTSL VEMKNLNEII FMNNGLNSCL PADIGRLKNV TVFDVSFNEL
VGPLPESVGG MVEVEQLNVA HNLLSGKIPA SICQLPKLEN FTYSYNFFTG EAPVCLRLSE
FDDRRNCLPG RPAQRSSRQC SAFLSRPSVD CGSFGCGRSV VKPSPPIVAL PPPPPPSPPL
PPPVYSPPPS PPVFSPPPSP PVYSPPPPPS IHYSSPPPPP VHHSSPPPPS PEFEGPLPPV
IGVSYASPPP PPFY
