LRX6_ARATH
ID LRX6_ARATH Reviewed; 470 AA.
AC Q9LUI1;
DT 13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Leucine-rich repeat extensin-like protein 6;
DE Short=AtLRX6;
DE Short=LRR/EXTENSIN6;
DE AltName: Full=Cell wall hydroxyproline-rich glycoprotein;
DE Flags: Precursor;
GN Name=LRX6; OrderedLocusNames=At3g22800; ORFNames=MWI23.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA de los Reyes C., Quan R., Chen H., Bautista V., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12644681; DOI=10.1104/pp.102.014928;
RA Baumberger N., Doesseger B., Guyot R., Diet A., Parsons R.L., Clark M.A.,
RA Simmons M.P., Bedinger P., Goff S.A., Ringli C., Keller B.;
RT "Whole-genome comparison of leucine-rich repeat extensins in Arabidopsis
RT and rice. A conserved family of cell wall proteins form a vegetative and a
RT reproductive clade.";
RL Plant Physiol. 131:1313-1326(2003).
CC -!- FUNCTION: Modulates cell morphogenesis by regulating cell wall
CC formation and assembly, and/or growth polarization. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:12644681}.
CC -!- DEVELOPMENTAL STAGE: Observed in emerging secondary roots.
CC {ECO:0000269|PubMed:12644681}.
CC -!- PTM: Hydroxylated on proline residues in the S-P-P-P-P repeat.
CC {ECO:0000250}.
CC -!- PTM: O-glycosylated on hydroxyprolines. {ECO:0000250}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB022223; BAB01255.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76678.1; -; Genomic_DNA.
DR EMBL; BT053757; ACL13984.1; -; mRNA.
DR RefSeq; NP_188919.1; NM_113179.4.
DR AlphaFoldDB; Q9LUI1; -.
DR SMR; Q9LUI1; -.
DR STRING; 3702.AT3G22800.1; -.
DR PaxDb; Q9LUI1; -.
DR PRIDE; Q9LUI1; -.
DR ProteomicsDB; 238577; -.
DR EnsemblPlants; AT3G22800.1; AT3G22800.1; AT3G22800.
DR GeneID; 821851; -.
DR Gramene; AT3G22800.1; AT3G22800.1; AT3G22800.
DR KEGG; ath:AT3G22800; -.
DR Araport; AT3G22800; -.
DR TAIR; locus:2094389; AT3G22800.
DR eggNOG; ENOG502QTD8; Eukaryota.
DR HOGENOM; CLU_000288_23_5_1; -.
DR InParanoid; Q9LUI1; -.
DR OMA; INPCSAH; -.
DR OrthoDB; 826997at2759; -.
DR PhylomeDB; Q9LUI1; -.
DR PRO; PR:Q9LUI1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LUI1; baseline and differential.
DR Genevisible; Q9LUI1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005199; F:structural constituent of cell wall; ISS:TAIR.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Glycoprotein; Hydroxylation;
KW Leucine-rich repeat; Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..470
FT /note="Leucine-rich repeat extensin-like protein 6"
FT /id="PRO_0000395466"
FT REPEAT 98..122
FT /note="LRR 1"
FT REPEAT 123..146
FT /note="LRR 2"
FT REPEAT 147..170
FT /note="LRR 3"
FT REPEAT 171..194
FT /note="LRR 4"
FT REPEAT 196..217
FT /note="LRR 5"
FT REPEAT 219..241
FT /note="LRR 6"
FT REPEAT 243..265
FT /note="LRR 7"
FT REPEAT 266..290
FT /note="LRR 8"
FT REPEAT 291..314
FT /note="LRR 9"
FT REPEAT 316..337
FT /note="LRR 10"
FT REGION 378..470
FT /note="Contains the Ser-Pro(4) repeats"
FT REGION 378..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 83
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 319
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 470 AA; 52335 MW; 5F3B812A60282D39 CRC64;
MREDTFFFQW WFLVSGLSFI FLLPQAFTYH TPPINPCFAH PFLPPITNPR LLKAFTALQA
WKFTITSDPN GFTSNWCGPN VCNYTGVFCA PALDNPYVLT VAGIDLNHAN IAGYLPLELG
LLTDLALFHI NSNRFQGQLP KTLKCLHLLH ELDVSNNKLS GEFPSVIFSL PSLKFLDIRF
NEFQGDVPSQ LFDLNLDALF INDNKFQFRL PRNIGNSPVS VLVLANNDLQ GSCVPPSFYK
MGKTLHEIII TNSQLTGCLN REIGLLNQLT VFDVSYNNLV GSLPETIGDM KSLEQLNIAH
NKFSGYIPES ICRLPRLENF TYSYNFFSGE PPACLRLQEF DDRRNCLPSR PMQRSLAECK
SFSSYPIDCA SFGCSPPSPP PPPPPPPPPP PPPPPPPPPP PPPPPPPYVY PSPPPPPPSP
PPYVYPPPPP PYVYPPPPSP PYVYPPPPPS PQPYMYPSPP CNDLPTPVHY
