ID   LS14B_XENTR             Reviewed;         382 AA.
AC   Q566L7;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Protein LSM14 homolog B;
DE   AltName: Full=Protein FAM61B homolog;
DE   AltName: Full=RNA-associated protein 55B;
DE            Short=RAP55B;
GN   Name=lsm14b; Synonyms=fam61b, rap55b;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the storage of translationally inactive
CC       mRNAs and protect them from degradation (By similarity). Plays a role
CC       in control of mRNA translation (By similarity).
CC       {ECO:0000250|UniProtKB:Q68FI1, ECO:0000250|UniProtKB:Q8CGC4}.
CC   -!- SUBUNIT: Component of a ribonucleoprotein (RNP) complex, at least
CC       composed of cpeb1, lsm14b/rap55b, ddx6/Xp54, ybx2/frgy2, pat1/P100,
CC       eif4enif1/4E-T and eif4e1b. Different translationally-repressed mRNP
CC       complexes probably exist that contain either lsm14a/rap55a or
CC       lsm14b/rap55b depending on the developmental stage. Component of a
CC       ribonucleoprotein (RNP) complex, composed at least of elavl1/elrA
CC       and/or elavl2/elrB, igf2bp3/vg1RBP, ddx6/Xp54, ybx2/frgy2,
CC       lsm14b/rap55b and, in a subset of RNP complexes, stau1/staufen (By
CC       similarity). {ECO:0000250|UniProtKB:Q68FI1}.
CC   -!- SIMILARITY: Belongs to the LSM14 family. {ECO:0000305}.
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DR   EMBL; BC093463; AAH93463.1; -; mRNA.
DR   RefSeq; NP_001025676.1; NM_001030505.1.
DR   AlphaFoldDB; Q566L7; -.
DR   SMR; Q566L7; -.
DR   DNASU; 595068; -.
DR   GeneID; 595068; -.
DR   KEGG; xtr:595068; -.
DR   CTD; 149986; -.
DR   Xenbase; XB-GENE-5893304; lsm14b.
DR   HOGENOM; CLU_019221_0_1_1; -.
DR   InParanoid; Q566L7; -.
DR   OrthoDB; 1569369at2759; -.
DR   Proteomes; UP000008143; Chromosome 10.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000001997; Expressed in 4-cell stage embryo and 12 other tissues.
DR   GO; GO:1990904; C:ribonucleoprotein complex; ISS:UniProtKB.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   CDD; cd01736; LSm14_N; 1.
DR   InterPro; IPR025762; DFDF.
DR   InterPro; IPR019050; FDF_dom.
DR   InterPro; IPR025761; FFD_box.
DR   InterPro; IPR025609; Lsm14-like_N.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR025768; TFG_box.
DR   Pfam; PF09532; FDF; 1.
DR   Pfam; PF12701; LSM14; 1.
DR   SMART; SM01199; FDF; 1.
DR   SMART; SM01271; LSM14; 1.
DR   SUPFAM; SSF50182; SSF50182; 1.
DR   PROSITE; PS51512; DFDF; 1.
DR   PROSITE; PS51513; FFD; 1.
DR   PROSITE; PS51536; TFG; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Reference proteome; Ribonucleoprotein;
KW   Translation regulation.
FT   CHAIN           1..382
FT                   /note="Protein LSM14 homolog B"
FT                   /id="PRO_0000187095"
FT   DOMAIN          238..274
FT                   /note="DFDF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00845"
FT   REGION          164..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          270..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          354..382
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           300..302
FT                   /note="FDF"
FT   MOTIF           309..325
FT                   /note="FFD box"
FT   MOTIF           327..347
FT                   /note="TFG box"
FT   COMPBIAS        164..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..291
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..382
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   382 AA;  42213 MW;  D6255A0A8E4DD410 CRC64;
     MSSGTPYIGS KISLISKAQI RYEGILYTID TENSTVALAK VRSFGTEDRP TDRPAPPREE
     VYEYIIFRGS DIKDITVCEP PKASHALPQD PAIVQSSLGS APSASYQSSV PYSPFRGMPT
     YSQLAASSLL SQQYAASLGL AGFPSIPLRK SPMVEQAVQT GPLESQAQKK VQQAKGAPVN
     QRGIRQSGPQ SQPAPLNVPP AAAPVLGTVN DENRRPPRRR SGNRRTRNRS RGQNRPTTVK
     ENAIKFEGDF DFETANAQFN REELDKEFKD KLNFKDEKPE KEGEEKTDSG VETQNSDGNP
     EEDPLGPNIY YDRSKSFFDN ISSEMKSRRT TWAEERKLNT ETFGVSGRFL RGRSFRGGFR
     GGRGSATPRR NQTTQRAGTG RV