LSD1_ORYSJ
ID LSD1_ORYSJ Reviewed; 184 AA.
AC Q0J7V9; A0A0N7KPB1; Q6QUK7; Q704V4;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Protein LSD1;
DE AltName: Full=Protein LESION SIMULATING DISEASE 1;
DE Short=OsLSD1;
DE AltName: Full=Putative zinc finger LSD1;
GN Name=LSD1; OrderedLocusNames=Os08g0159500, LOC_Os08g06280;
GN ORFNames=OsJ_26122;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION, SUBCELLULAR LOCATION, AND
RP INDUCTION BY LIGHT.
RC STRAIN=cv. Nipponbare;
RX PubMed=15915636; DOI=10.1094/mpmi-18-0375;
RA Wang L., Pei Z., Tian Y., He C.;
RT "OsLSD1, a rice zinc finger protein, regulates programmed cell death and
RT callus differentiation.";
RL Mol. Plant Microbe Interact. 18:375-384(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RC TISSUE=Leaf;
RA Huang J., Huang F., Zhang H.S.;
RT "A LSD1-like zinc finger protein cDNA from rice.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Negative regulator of programmed cell death and
CC hypersensitive response (HR). Positive regulator of callus
CC differentiation. {ECO:0000269|PubMed:15915636}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15915636}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q0J7V9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q0J7V9-2; Sequence=VSP_041106;
CC -!- INDUCTION: By light. Down-regulated by dark.
CC {ECO:0000269|PubMed:15915636}.
CC -!- MISCELLANEOUS: Plants silencing LSD1 display a lesion-mimic phenotype,
CC increased pathogen induction of PR1, enhanced resistance to virulent
CC rice blast fungus and accelerated and intensified hypersensitive
CC response to avirulent pathogens. Plants overexpressing LSD1 show
CC increased content of chlorophyll b and enhanced resistance to virulent
CC rice blast fungus. Callus overexpressing LSD1 shows accelerated
CC differentiation and plant regeneration.
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DR EMBL; AY525368; AAS13688.1; -; mRNA.
DR EMBL; AJ620676; CAF05902.1; -; mRNA.
DR EMBL; AP008214; BAF22956.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT03922.1; -; Genomic_DNA.
DR EMBL; CM000145; EEE68083.1; -; Genomic_DNA.
DR EMBL; AK111759; BAG99402.1; -; mRNA.
DR EMBL; AK111759; BAG99403.1; -; mRNA.
DR RefSeq; XP_015648108.1; XM_015792622.1. [Q0J7V9-2]
DR RefSeq; XP_015648109.1; XM_015792623.1. [Q0J7V9-2]
DR RefSeq; XP_015648110.1; XM_015792624.1. [Q0J7V9-2]
DR RefSeq; XP_015648111.1; XM_015792625.1. [Q0J7V9-2]
DR AlphaFoldDB; Q0J7V9; -.
DR STRING; 4530.OS08T0159500-01; -.
DR PaxDb; Q0J7V9; -.
DR PRIDE; Q0J7V9; -.
DR EnsemblPlants; Os08t0159500-01; Os08t0159500-01; Os08g0159500. [Q0J7V9-1]
DR GeneID; 4344713; -.
DR Gramene; Os08t0159500-01; Os08t0159500-01; Os08g0159500. [Q0J7V9-1]
DR KEGG; osa:4344713; -.
DR eggNOG; ENOG502RY0V; Eukaryota.
DR HOGENOM; CLU_111765_0_0_1; -.
DR InParanoid; Q0J7V9; -.
DR OMA; ARICEAS; -.
DR OrthoDB; 1480977at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR ExpressionAtlas; Q0J7V9; baseline and differential.
DR Genevisible; Q0J7V9; OS.
DR GO; GO:0005634; C:nucleus; TAS:UniProtKB.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0031348; P:negative regulation of defense response; IMP:UniProtKB.
DR GO; GO:0034051; P:negative regulation of plant-type hypersensitive response; IMP:UniProtKB.
DR GO; GO:0009626; P:plant-type hypersensitive response; IEA:UniProtKB-KW.
DR GO; GO:0045595; P:regulation of cell differentiation; IMP:UniProtKB.
DR InterPro; IPR040319; LSD1-like.
DR InterPro; IPR036280; Multihaem_cyt_sf.
DR InterPro; IPR005735; Znf_LSD1.
DR PANTHER; PTHR31747; PTHR31747; 1.
DR Pfam; PF06943; zf-LSD1; 3.
DR SUPFAM; SSF48695; SSF48695; 1.
DR TIGRFAMs; TIGR01053; LSD1; 3.
PE 2: Evidence at transcript level;
KW Alternative splicing; Apoptosis; Differentiation; Hypersensitive response;
KW Nucleus; Plant defense; Reference proteome.
FT CHAIN 1..184
FT /note="Protein LSD1"
FT /id="PRO_0000408486"
FT REGION 65..95
FT /note="Putative zinc finger 1"
FT REGION 104..134
FT /note="Putative zinc finger 2"
FT REGION 142..172
FT /note="Putative zinc finger 3"
FT VAR_SEQ 1..41
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764,
FT ECO:0000303|PubMed:15915636, ECO:0000303|Ref.2"
FT /id="VSP_041106"
FT CONFLICT 178
FT /note="T -> I (in Ref. 1; AAS13688)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 184 AA; 19021 MW; 264107A232807D5A CRC64;
MHLSAGFLSC RERKGDFSCL TAARICEAST SDAVVQAAGT AMPVPLAPYP TPPVPFTPPN
GAQSQLVCSG CRNLLMYPAG ATSVCCAVCS TVTAVPAPGT EMAQLVCGGC HTLLMYIRGA
TSVQCSCCHT VNLAMEANQV AHVNCGNCRM LLMYQYGARS VKCAVCNFVT SVGASPGTDQ
KPSS
