LSG1_HAEIN
ID LSG1_HAEIN Reviewed; 401 AA.
AC P71399; Q48210;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 2.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Lsg locus putative protein 1;
GN OrderedLocusNames=HI_1700;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=A2;
RA McLaughlin R., Abu Kwaik Y., Young R., Spinola S., Apicella M.;
RT "Characterization and sequence of the lsg locus from Haemophilus
RT influenzae.";
RL Submitted (JUN-1992) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC HI_0867/HI_1700 subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC23346.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; M94855; AAA24978.1; -; Genomic_DNA.
DR EMBL; L42023; AAC23346.1; ALT_INIT; Genomic_DNA.
DR PIR; H64175; H64175.
DR RefSeq; NP_439842.2; NC_000907.1.
DR RefSeq; WP_005694190.1; NC_000907.1.
DR AlphaFoldDB; P71399; -.
DR SMR; P71399; -.
DR STRING; 71421.HI_1700; -.
DR EnsemblBacteria; AAC23346; AAC23346; HI_1700.
DR KEGG; hin:HI_1700; -.
DR PATRIC; fig|71421.8.peg.1779; -.
DR eggNOG; COG2244; Bacteria.
DR HOGENOM; CLU_022017_7_0_6; -.
DR PhylomeDB; P71399; -.
DR BioCyc; HINF71421:G1GJ1-1716-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002797; Polysacc_synth.
DR Pfam; PF01943; Polysacc_synt; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..401
FT /note="Lsg locus putative protein 1"
FT /id="PRO_0000166456"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 249
FT /note="V -> I (in Ref. 1; AAA24978)"
FT /evidence="ECO:0000305"
FT CONFLICT 276
FT /note="V -> I (in Ref. 1; AAA24978)"
FT /evidence="ECO:0000305"
FT CONFLICT 358
FT /note="I -> V (in Ref. 1; AAA24978)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 401 AA; 45945 MW; FE2E7B02747B0874 CRC64;
MKVFKDSVIY LVGELSSKLV PFLLLPYLSR KLGVEGYGSL SYYQTFLSLF LIVVSLTQEG
AISRYFYFYG KRSLNLVVNT GYAYTTIIGS IILIGCWIAQ SEILFYAALS SIFQSFLNVQ
LSVRQCQKKA WSYAFIQFSL TVTGAVFTVA LLEYYQNDLV EKRILAILLS NLVVWFFSYF
LYRKSTTSKK YQFKHYQSAL FYILGFGLPL ILHYASFFLK GQLDRIFIYH KFSETDLGLY
AMGAQLALVV SIAIQALNKA IIPYFYEALK QKKLVVQQLH KWALFSFLLI PIPALIMWII
PEDVLVWILG SQFVGTKYYF ILFLISTTLS IPYLILVNYL FYYGKNKLIS QCSVLSTIIY
VASLVALTFT EIKYIPYAGI IGSLSIIPIL YFMTSKVSKT L
