LSH8_ARATH
ID LSH8_ARATH Reviewed; 164 AA.
AC Q9FZ51;
DT 19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 8;
DE AltName: Full=Protein ORGAN BOUNDARY 8;
GN Name=LSH8; Synonyms=OBO8; OrderedLocusNames=At1g16910;
GN ORFNames=F17F16.11, F6I1.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=16244158; DOI=10.1104/pp.105.063479;
RA Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT reveals numerous transcript variants.";
RL Plant Physiol. 139:1323-1337(2005).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=14871309; DOI=10.1111/j.1365-313x.2003.01993.x;
RA Zhao L., Nakazawa M., Takase T., Manabe K., Kobayashi M., Seki M.,
RA Shinozaki K., Matsui M.;
RT "Overexpression of LSH1, a member of an uncharacterised gene family, causes
RT enhanced light regulation of seedling development.";
RL Plant J. 37:694-706(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=21245300; DOI=10.1073/pnas.1018542108;
RA Cho E., Zambryski P.C.;
RT "Organ boundary1 defines a gene expressed at the junction between the shoot
RT apical meristem and lateral organs.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2154-2159(2011).
RN [6]
RP DNA-BINDING, AND GENE FAMILY.
RX PubMed=23146749; DOI=10.1186/1745-6150-7-39;
RA Iyer L.M., Aravind L.;
RT "ALOG domains: provenance of plant homeotic and developmental regulators
RT from the DNA-binding domain of a novel class of DIRS1-type retroposons.";
RL Biol. Direct 7:39-39(2012).
CC -!- FUNCTION: Probable transcription regulator that acts as a developmental
CC regulator by promoting cell growth in response to light. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the plant homeotic and developmental regulators
CC ALOG protein family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC051629; AAF99841.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29520.1; -; Genomic_DNA.
DR EMBL; AY800583; AAV68819.1; -; mRNA.
DR PIR; F86304; F86304.
DR RefSeq; NP_173135.1; NM_101552.3.
DR AlphaFoldDB; Q9FZ51; -.
DR STRING; 3702.AT1G16910.1; -.
DR PaxDb; Q9FZ51; -.
DR PRIDE; Q9FZ51; -.
DR ProteomicsDB; 238501; -.
DR EnsemblPlants; AT1G16910.1; AT1G16910.1; AT1G16910.
DR GeneID; 838262; -.
DR Gramene; AT1G16910.1; AT1G16910.1; AT1G16910.
DR KEGG; ath:AT1G16910; -.
DR Araport; AT1G16910; -.
DR TAIR; locus:2015591; AT1G16910.
DR eggNOG; ENOG502QQTQ; Eukaryota.
DR HOGENOM; CLU_071168_1_1_1; -.
DR InParanoid; Q9FZ51; -.
DR PhylomeDB; Q9FZ51; -.
DR PRO; PR:Q9FZ51; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FZ51; baseline and differential.
DR Genevisible; Q9FZ51; AT.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009299; P:mRNA transcription; ISS:UniProtKB.
DR GO; GO:0090698; P:post-embryonic plant morphogenesis; ISS:UniProtKB.
DR GO; GO:0009416; P:response to light stimulus; IBA:GO_Central.
DR InterPro; IPR040222; ALOG.
DR InterPro; IPR006936; ALOG_dom.
DR PANTHER; PTHR31165; PTHR31165; 1.
DR Pfam; PF04852; DUF640; 1.
DR PROSITE; PS51697; ALOG; 1.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..164
FT /note="Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 8"
FT /id="PRO_0000425295"
FT DOMAIN 23..150
FT /note="ALOG"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01033"
FT MOTIF 148..152
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250"
SQ SEQUENCE 164 AA; 18524 MW; FAEC3C2B7A191DDD CRC64;
MTSTNTRNKG KCIVEGPPPT LSRYESQKSR DWNTFCQYLM TKMPPVHVWE CESNHILDFL
QSRDQFGKTK VHIQGCVFFG QKEPPGECNC PLKQAWGSLD ALIGRLRAAY EENGGLTEKN
PFARGGIRIF LREVRGSQAK ARGVLYKKKK RLVVVGTGTS TTWT
