ID   LSRB_ENT38              Reviewed;         333 AA.
AC   A4WER1;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Autoinducer 2-binding protein LsrB;
DE            Short=AI-2-binding protein LsrB;
DE   Flags: Precursor;
GN   Name=lsrB; OrderedLocusNames=Ent638_3533;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC       LsrD permeases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000653; ABP62191.1; -; Genomic_DNA.
DR   RefSeq; WP_015960517.1; NC_009436.1.
DR   AlphaFoldDB; A4WER1; -.
DR   SMR; A4WER1; -.
DR   STRING; 399742.Ent638_3533; -.
DR   EnsemblBacteria; ABP62191; ABP62191; Ent638_3533.
DR   KEGG; ent:Ent638_3533; -.
DR   eggNOG; COG1879; Bacteria.
DR   HOGENOM; CLU_037628_3_0_6; -.
DR   OMA; KQVNNPY; -.
DR   OrthoDB; 669710at2; -.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR   InterPro; IPR030159; LsrB.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..333
FT                   /note="Autoinducer 2-binding protein LsrB"
FT                   /id="PRO_5000238166"
SQ   SEQUENCE   333 AA;  35768 MW;  446F7925A47329F9 CRC64;
     MKTKLLVLAV ALSVASAQAA DRIAFIPKLV GVGFFTSGGN GAKEAGKELG VDVTYDGPTE
     PSVSGQVQLI NNFVNQGFNA IIVSAVSPDG LCPALKRAMQ RGVKVLTWDS DTKPECRSIY
     INQGTPEQLG SLLVDMASKQ VTKPAAKVAF FYSSPTVTDQ NQWVKEAKAK IEKEHPQWQV
     VTTQFGYNDA TKSLQTAEGI LKAYPDLDAI IAPDANALPA AAQATENLKR EGVAIVGFST
     PNVMRPYVER GTVKAFGLWD VVQQGKIAVN VADHLLKKGD LNVGDSVDVK GIGVLKVEPN
     SVQGYQYEAK GNGIVLLPER VVFTKENIDK YDF