ID   LSRB_PHOLL              Reviewed;         339 AA.
AC   Q7MB18;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Autoinducer 2-binding protein LsrB;
DE            Short=AI-2-binding protein LsrB;
DE   Flags: Precursor;
GN   Name=lsrB; OrderedLocusNames=plu3146;
OS   Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS   TT01).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=243265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15139 / CIP 105565 / TT01;
RX   PubMed=14528314; DOI=10.1038/nbt886;
RA   Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA   Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA   Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA   Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA   Glaser P., Boemare N., Danchin A., Kunst F.;
RT   "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT   luminescens.";
RL   Nat. Biotechnol. 21:1307-1313(2003).
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC       LsrD permeases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; BX571869; CAE15520.1; -; Genomic_DNA.
DR   RefSeq; WP_011147357.1; NC_005126.1.
DR   AlphaFoldDB; Q7MB18; -.
DR   SMR; Q7MB18; -.
DR   STRING; 243265.plu3146; -.
DR   EnsemblBacteria; CAE15520; CAE15520; plu3146.
DR   GeneID; 24170036; -.
DR   KEGG; plu:plu3146; -.
DR   eggNOG; COG1879; Bacteria.
DR   HOGENOM; CLU_037628_3_0_6; -.
DR   OMA; KQVNNPY; -.
DR   OrthoDB; 669710at2; -.
DR   BioCyc; PLUM243265:PLU_RS15660-MON; -.
DR   Proteomes; UP000002514; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR   InterPro; IPR030159; LsrB.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..339
FT                   /note="Autoinducer 2-binding protein LsrB"
FT                   /id="PRO_0000351323"
SQ   SEQUENCE   339 AA;  36643 MW;  931CD66A64EE2C99 CRC64;
     MKTLILKKLA LISLLSLACA SWVHAAERIA FIPKLVGVGF FTSGGQGAVA AGKALGVNVT
     YDGPTEPSVA GQVQLINNFV NQGYNAIVVS AVSPDGLCPA LKRAMQRGVK ILTWDSDTSP
     ECRSIYINQG TPNQLGGMLV DMAANQVQKK QAKVAFFYSS PTVTDQNQWV KEAKDKIAAE
     HPGWEIVTTQ FGYNDATKSL QTAEGILKAW SDLDAIIAPD ANALPAAAQA AENLKRQNVA
     IVGFSTPNVM RPYVERGTVK QFGLWDVVNQ GKISIHVANE LLKKGDLNVG DKLDIPDIGM
     VEVVPNRVQG YRYEAKGNGI VVLPERVIFT KDNINQYDF