ID   LSRB_PHOLU              Reviewed;         339 AA.
AC   Q2PBL7;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=Autoinducer 2-binding protein LsrB;
DE            Short=AI-2-binding protein LsrB;
DE   Flags: Precursor;
GN   Name=lsrB;
OS   Photorhabdus luminescens (Xenorhabdus luminescens).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Photorhabdus.
OX   NCBI_TaxID=29488;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 29999 / DSM 3368 / BCRC 14801 / CIP 106429 / NCIMB 12670 / Hb;
RX   PubMed=16385072; DOI=10.1128/jb.188.2.809-814.2006;
RA   Gaudriault S., Duchaud E., Lanois A., Canoy A.-S., Bourot S., DeRose R.,
RA   Kunst F., Boemare N., Givaudan A.;
RT   "Whole-genome comparison between Photorhabdus strains to identify genomic
RT   regions involved in the specificity of nematode interaction.";
RL   J. Bacteriol. 188:809-814(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC       LsrD permeases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; AJ967010; CAI91193.1; -; Genomic_DNA.
DR   RefSeq; WP_049584342.1; NZ_FMWJ01000024.1.
DR   AlphaFoldDB; Q2PBL7; -.
DR   SMR; Q2PBL7; -.
DR   STRING; 29488.KS18_20650; -.
DR   GeneID; 45657230; -.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR   InterPro; IPR030159; LsrB.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..339
FT                   /note="Autoinducer 2-binding protein LsrB"
FT                   /id="PRO_0000351324"
SQ   SEQUENCE   339 AA;  36723 MW;  C50FD9A39BDEC6DE CRC64;
     MKTLILKKLA LISLLSLACA SWVHAAERIA FIPKLVGVGF FTSGGQGAVA AGKALGVNVT
     YDGPTEPSVA GQVQLINNFV NQGYNAIVVS AVSPDGLCPA LKRAMKRGVK ILTWDSDTSP
     ECRSIYINQG TPDQLGGMLV DMAANQVQKK QAKVAFFYSS PTVTDQNQWV KEAKDKIAAE
     HPDWEIVTTQ FGYNDATKSL QTAEGILKAW SDLDAIIAPD ANALPAAAQA AENLKRQNVA
     IVGFSTPNVM RPYVERGTVK QFGLWDVVNQ GKISIYIANE LLKKGDLNVG DKLDIPDIGI
     VEVVPNRVQG YRYEAKGNGI VVLPERVIFT KDNINQYNF