ID   LSRB_SALCH              Reviewed;         340 AA.
AC   Q57HE0;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Autoinducer 2-binding protein LsrB;
DE            Short=AI-2-binding protein LsrB;
DE   Flags: Precursor;
GN   Name=lsrB; OrderedLocusNames=SCH_3966;
OS   Salmonella choleraesuis (strain SC-B67).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=321314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-B67;
RX   PubMed=15781495; DOI=10.1093/nar/gki297;
RA   Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA   Lee Y.-S.;
RT   "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT   invasive and resistant zoonotic pathogen.";
RL   Nucleic Acids Res. 33:1690-1698(2005).
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC       LsrD permeases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
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DR   EMBL; AE017220; AAX67872.1; -; Genomic_DNA.
DR   RefSeq; WP_011264437.1; NC_006905.1.
DR   AlphaFoldDB; Q57HE0; -.
DR   SMR; Q57HE0; -.
DR   EnsemblBacteria; AAX67872; AAX67872; SCH_3966.
DR   KEGG; sec:SCH_3966; -.
DR   HOGENOM; CLU_037628_3_0_6; -.
DR   OMA; KQVNNPY; -.
DR   Proteomes; UP000000538; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR   InterPro; IPR030159; LsrB.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..340
FT                   /note="Autoinducer 2-binding protein LsrB"
FT                   /id="PRO_0000351326"
SQ   SEQUENCE   340 AA;  36818 MW;  127A9AA57562A93F CRC64;
     MARHSIKMIA LLTAFGLASA AMTVQAAERI AFIPKLVGVG FFTSGGNGAQ EAGKALGIDV
     TYDGPTEPSV SGQVQLVNNF VNQGYDAIIV SAVSPDGLCP ALKRAMQRGV KILTWDSDTK
     PECRSYYINQ GTPKQLGSML VEMAAHQVDK EKAKVAFFYS SPTVTDQNQW VKEAKAKISK
     EHPGWEIVTT QFGYNDATKS LQTAEGIIKA YPDLDAIIAP DANALPAAAQ AAENLKRNNL
     AIVGFSTPNV MRPYVQRGTV KEFGLWDVVQ QGKISVYVAN ELLKNMPMNV GDSLDIPGIG
     KVTVSPNSEQ GYHYEAKGNG IVLLPERVIF NKDNIDKYDF