ID   LSRB_SALPB              Reviewed;         340 AA.
AC   A9MZG4;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 2.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Autoinducer 2-binding protein LsrB;
DE            Short=AI-2-binding protein LsrB;
DE   Flags: Precursor;
GN   Name=lsrB; OrderedLocusNames=SPAB_05051;
OS   Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=1016998;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1250 / SPB7;
RG   The Salmonella enterica serovar Paratyphi B Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Part of the ABC transporter complex LsrABCD involved in
CC       autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and
CC       LsrD permeases (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (LsrA),
CC       two transmembrane proteins (LsrC and LsrD) and a solute-binding protein
CC       (LsrB). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 2 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABX70342.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000886; ABX70342.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000090740.1; NC_010102.1.
DR   AlphaFoldDB; A9MZG4; -.
DR   SMR; A9MZG4; -.
DR   KEGG; spq:SPAB_05051; -.
DR   PATRIC; fig|1016998.12.peg.4741; -.
DR   HOGENOM; CLU_037628_3_0_6; -.
DR   BioCyc; SENT1016998:SPAB_RS20555-MON; -.
DR   Proteomes; UP000008556; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:UniProt.
DR   CDD; cd20003; PBP1_LsrB_Quorum_Sensing; 1.
DR   InterPro; IPR030159; LsrB.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR46847:SF4; PTHR46847:SF4; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
PE   3: Inferred from homology;
KW   Periplasm; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..340
FT                   /note="Autoinducer 2-binding protein LsrB"
FT                   /id="PRO_0000351328"
SQ   SEQUENCE   340 AA;  36787 MW;  E68C61815B49B419 CRC64;
     MARHSIKMIA LLTAFGLASA VMTVQAAERI AFIPKLVGVG FFTSGGNGAQ EAGKALGIDV
     TYDGPTEPSV SGQVQLVNNF VNQGYDAIIV SAVSPDGLCP ALKRAMQRGV KILTWDSDTK
     PECRSYYINQ GTPKQLGSML VEMAAHQVDK EKAKVAFFYS SPTVTDQNQW VKEAKAKISQ
     EHPGWEIVTT QFGYNDATKS LQTAEGIIKA YPDLDAIIAP DANALPAAAQ AAENLKRNNL
     AIVGFSTPNV MRPYVQRGTV KEFGLWDVVQ QGKISVYVAN ALLKNMPMNV GDSLDIPGIG
     KVTVSPNSEQ GYHYEAKGNG IVLLPERVIF NKNNIDKYDF